Amino-acid racemase

In enzymology, an amino-acid racemase (EC number|5.1.1.10) is an enzyme that catalyzes the chemical reaction

:an L-amino acid $ightleftharpoons$ a D-amino acid

Hence, this enzyme has one substrate, L-amino acid, and one product, D-amino acid.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on amino acids and derivatives. The systematic name of this enzyme class is amino-acid racemase. This enzyme is also called L-amino acid racemase. This enzyme participates in 4 metabolic pathways: glycine, serine and threonine metabolism, cysteine metabolism, D-glutamine and D-glutamate metabolism, and D-arginine and D-ornithine metabolism. It employs one cofactor, pyridoxal phosphate.

tructural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2FKP, PDB link|2GGG, PDB link|2GGH, PDB link|2GGI, and PDB link|2GGJ.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9068-61-5."

Gene Ontology (GO) codes