Podocalyxin

Podocalyxin

Podocalyxin, a sialoglycoprotein, is thought to be the major constituent of the glycocalyx of podocytes [ [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602632 Omim - Podocalyxin-Like; Podxl ] ] . It coats the secondary foot processes of the podocytes. It is negatively charged and thus functions to keep adjacent foot processes separated, thereby keeping the urinary filtration barrier open. [cite book |last=Gartner |first=LP |coauthors=Hiatt, Strum |title=Cell Biology and Histology |year=2007 |publisher=Lippincott Williams and Wilkins |location= |language= |isbn=978-0-7817-8577-8]

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