RAD23B

RAD23B

RAD23 homolog B (S. cerevisiae), also known as RAD23B, is a human gene.

PBB_Summary
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summary_text = The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.cite web | title = Entrez Gene: RAD23B RAD23 homolog B (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5887| accessdate = ]

References

Further reading

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citations =
*cite journal | author=van der Spek PJ, Smit EM, Beverloo HB, "et al." |title=Chromosomal localization of three repair genes: the xeroderma pigmentosum group C gene and two human homologs of yeast RAD23. |journal=Genomics |volume=23 |issue= 3 |pages= 651–8 |year= 1995 |pmid= 7851894 |doi= 10.1006/geno.1994.1554
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Masutani C, Sugasawa K, Yanagisawa J, "et al." |title=Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23. |journal=EMBO J. |volume=13 |issue= 8 |pages= 1831–43 |year= 1994 |pmid= 8168482 |doi=
*cite journal | author=van der Spek PJ, Eker A, Rademakers S, "et al." |title=XPC and human homologs of RAD23: intracellular localization and relationship to other nucleotide excision repair complexes. |journal=Nucleic Acids Res. |volume=24 |issue= 13 |pages= 2551–9 |year= 1996 |pmid= 8692695 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Sugasawa K, Ng JM, Masutani C, "et al." |title=Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. |journal=Mol. Cell |volume=2 |issue= 2 |pages= 223–32 |year= 1998 |pmid= 9734359 |doi=
*cite journal | author=Hiyama H, Yokoi M, Masutani C, "et al." |title=Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome. |journal=J. Biol. Chem. |volume=274 |issue= 39 |pages= 28019–25 |year= 1999 |pmid= 10488153 |doi=
*cite journal | author=Miao F, Bouziane M, Dammann R, "et al." |title=3-Methyladenine-DNA glycosylase (MPG protein) interacts with human RAD23 proteins. |journal=J. Biol. Chem. |volume=275 |issue= 37 |pages= 28433–8 |year= 2000 |pmid= 10854423 |doi= 10.1074/jbc.M001064200
*cite journal | author=Wang G, Sawai N, Kotliarova S, "et al." |title=Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23, HHR23A and HHR23B. |journal=Hum. Mol. Genet. |volume=9 |issue= 12 |pages= 1795–803 |year= 2000 |pmid= 10915768 |doi=
*cite journal | author=Araújo SJ, Nigg EA, Wood RD |title=Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome. |journal=Mol. Cell. Biol. |volume=21 |issue= 7 |pages= 2281–91 |year= 2001 |pmid= 11259578 |doi= 10.1128/MCB.21.7.2281-2291.2001
*cite journal | author=Araki M, Masutani C, Takemura M, "et al." |title=Centrosome protein centrin 2/caltractin 1 is part of the xeroderma pigmentosum group C complex that initiates global genome nucleotide excision repair. |journal=J. Biol. Chem. |volume=276 |issue= 22 |pages= 18665–72 |year= 2001 |pmid= 11279143 |doi= 10.1074/jbc.M100855200
*cite journal | author=Park H, Suzuki T, Lennarz WJ |title=Identification of proteins that interact with mammalian peptide:N-glycanase and implicate this hydrolase in the proteasome-dependent pathway for protein degradation. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 20 |pages= 11163–8 |year= 2001 |pmid= 11562482 |doi= 10.1073/pnas.201393498
*cite journal | author=Walters KJ, Kleijnen MF, Goh AM, "et al." |title=Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a. |journal=Biochemistry |volume=41 |issue= 6 |pages= 1767–77 |year= 2002 |pmid= 11827521 |doi=
*cite journal | author=Lee SM, Li ML, Tse YC, "et al." |title=Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway. |journal=Life Sci. |volume=71 |issue= 19 |pages= 2267–77 |year= 2002 |pmid= 12215374 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Shimizu Y, Iwai S, Hanaoka F, Sugasawa K |title=Xeroderma pigmentosum group C protein interacts physically and functionally with thymine DNA glycosylase. |journal=EMBO J. |volume=22 |issue= 1 |pages= 164–73 |year= 2003 |pmid= 12505994 |doi= 10.1093/emboj/cdg016
*cite journal | author=Ng JM, Vermeulen W, van der Horst GT, "et al." |title=A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein. |journal=Genes Dev. |volume=17 |issue= 13 |pages= 1630–45 |year= 2003 |pmid= 12815074 |doi= 10.1101/gad.260003
*cite journal | author=Ryu KS, Lee KJ, Bae SH, "et al." |title=Binding surface mapping of intra- and interdomain interactions among hHR23B, ubiquitin, and polyubiquitin binding site 2 of S5a. |journal=J. Biol. Chem. |volume=278 |issue= 38 |pages= 36621–7 |year= 2003 |pmid= 12832454 |doi= 10.1074/jbc.M304628200
*cite journal | author=Fujiwara K, Tenno T, Sugasawa K, "et al." |title=Structure of the ubiquitin-interacting motif of S5a bound to the ubiquitin-like domain of HR23B. |journal=J. Biol. Chem. |volume=279 |issue= 6 |pages= 4760–7 |year= 2004 |pmid= 14585839 |doi= 10.1074/jbc.M309448200
*cite journal | author=Glockzin S, Ogi FX, Hengstermann A, "et al." |title=Involvement of the DNA repair protein hHR23 in p53 degradation. |journal=Mol. Cell. Biol. |volume=23 |issue= 24 |pages= 8960–9 |year= 2004 |pmid= 14645509 |doi=

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