GAS6

Growth arrest-specific 6, also known as GAS6, is a human gene.

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summary_text = GAS6 is a gamma-carboxyglutamic acid (Gla) domain-containing protein thought to be involved in the stimulation of cell proliferationcite web | title = Entrez Gene: GAS6 growth arrest-specific 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2621| accessdate = ]

References

Further reading

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*cite journal | author=Maree AO, Jneid H, Palacios IF, "et al." |title=Growth arrest specific gene (GAS) 6 modulates platelet thrombus formation and vascular wall homeostasis and represents an attractive drug target. |journal=Curr. Pharm. Des. |volume=13 |issue= 26 |pages= 2656–61 |year= 2007 |pmid= 17897008 |doi=
*cite journal | author=Varnum BC, Young C, Elliott G, "et al." |title=Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6. |journal=Nature |volume=373 |issue= 6515 |pages= 623–6 |year= 1995 |pmid= 7854420 |doi= 10.1038/373623a0
*cite journal | author=Stitt TN, Conn G, Gore M, "et al." |title=The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases. |journal=Cell |volume=80 |issue= 4 |pages= 661–70 |year= 1995 |pmid= 7867073 |doi=
*cite journal | author=Manfioletti G, Brancolini C, Avanzi G, Schneider C |title=The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade. |journal=Mol. Cell. Biol. |volume=13 |issue= 8 |pages= 4976–85 |year= 1993 |pmid= 8336730 |doi=
*cite journal | author=Saccone S, Marcandalli P, Gostissa M, "et al." |title=Assignment of the human GAS6 gene to chromosome 13q34 by fluorescence in situ hybridization. |journal=Genomics |volume=30 |issue= 1 |pages= 129–31 |year= 1996 |pmid= 8595896 |doi= 10.1006/geno.1995.0027
*cite journal | author=Li R, Chen J, Hammonds G, "et al." |title=Identification of Gas6 as a growth factor for human Schwann cells. |journal=J. Neurosci. |volume=16 |issue= 6 |pages= 2012–9 |year= 1996 |pmid= 8604045 |doi=
*cite journal | author=Mark MR, Chen J, Hammonds RG, "et al." |title=Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and Axl. |journal=J. Biol. Chem. |volume=271 |issue= 16 |pages= 9785–9 |year= 1996 |pmid= 8621659 |doi=
*cite journal | author=Goruppi S, Ruaro E, Schneider C |title=Gas6, the ligand of Axl tyrosine kinase receptor, has mitogenic and survival activities for serum starved NIH3T3 fibroblasts. |journal=Oncogene |volume=12 |issue= 3 |pages= 471–80 |year= 1996 |pmid= 8637702 |doi=
*cite journal | author=Nagata K, Ohashi K, Nakano T, "et al." |title=Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases. |journal=J. Biol. Chem. |volume=271 |issue= 47 |pages= 30022–7 |year= 1997 |pmid= 8939948 |doi=
*cite journal | author=Loeser RF, Varnum BC, Carlson CS, "et al." |title=Human chondrocyte expression of growth-arrest-specific gene 6 and the tyrosine kinase receptor axl: potential role in autocrine signaling in cartilage. |journal=Arthritis Rheum. |volume=40 |issue= 8 |pages= 1455–65 |year= 1997 |pmid= 9259426 |doi= 10.1002/1529-0131(199708)40:8<1455::AID-ART14>3.0.CO;2-B
*cite journal | author=Marcandalli P, Gostissa M, Varnum B, "et al." |title=Identification and tissue expression of a splice variant for the growth arrest-specific gene gas6. |journal=FEBS Lett. |volume=415 |issue= 1 |pages= 56–8 |year= 1997 |pmid= 9326368 |doi=
*cite journal | author=Goruppi S, Yamane H, Marcandalli P, "et al." |title=The product of a gas6 splice variant allows the release of the domain responsible for Axl tyrosine kinase receptor activation. |journal=FEBS Lett. |volume=415 |issue= 1 |pages= 59–63 |year= 1997 |pmid= 9326369 |doi=
*cite journal | author=Nakano T, Ishimoto Y, Kishino J, "et al." |title=Cell adhesion to phosphatidylserine mediated by a product of growth arrest-specific gene 6. |journal=J. Biol. Chem. |volume=272 |issue= 47 |pages= 29411–4 |year= 1997 |pmid= 9367994 |doi=
*cite journal | author=Prieto AL, Weber JL, Lai C |title=Expression of the receptor protein-tyrosine kinases Tyro-3, Axl, and mer in the developing rat central nervous system. |journal=J. Comp. Neurol. |volume=425 |issue= 2 |pages= 295–314 |year= 2000 |pmid= 10954847 |doi=
*cite journal | author=Angelillo-Scherrer A, de Frutos P, Aparicio C, "et al." |title=Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis. |journal=Nat. Med. |volume=7 |issue= 2 |pages= 215–21 |year= 2001 |pmid= 11175853 |doi= 10.1038/84667
*cite journal | author=Sun WS, Misao R, Iwagaki S, "et al." |title=Coexpression of growth arrest-specific gene 6 and receptor tyrosine kinases, Axl and Sky, in human uterine endometrium and ovarian endometriosis. |journal=Mol. Hum. Reprod. |volume=8 |issue= 6 |pages= 552–8 |year= 2003 |pmid= 12029073 |doi=
*cite journal | author=Sasaki T, Knyazev PG, Cheburkin Y, "et al." |title=Crystal structure of a C-terminal fragment of growth arrest-specific protein Gas6. Receptor tyrosine kinase activation by laminin G-like domains. |journal=J. Biol. Chem. |volume=277 |issue= 46 |pages= 44164–70 |year= 2003 |pmid= 12218057 |doi= 10.1074/jbc.M207340200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ito M, Nakashima M, Nakayama T, "et al." |title=Expression of receptor-type tyrosine kinase, Axl, and its ligand, Gas6, in pediatric thyroid carcinomas around chernobyl. |journal=Thyroid |volume=12 |issue= 11 |pages= 971–5 |year= 2003 |pmid= 12490074 |doi= 10.1089/105072502320908303
*cite journal | author=Shankar SL, O'Guin K, Cammer M, "et al." |title=The growth arrest-specific gene product Gas6 promotes the survival of human oligodendrocytes via a phosphatidylinositol 3-kinase-dependent pathway. |journal=J. Neurosci. |volume=23 |issue= 10 |pages= 4208–18 |year= 2003 |pmid= 12764109 |doi=

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