- RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3, also known as RAPGEF3, is a human
gene . [cite web | title = Entrez Gene: RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10411| accessdate = ]PBB_Summary
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summary_text =References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Ehrhardt A, Ehrhardt GR, Guo X, Schrader JW |title=Ras and relatives--job sharing and networking keep an old family together. |journal=Exp. Hematol. |volume=30 |issue= 10 |pages= 1089–106 |year= 2002 |pmid= 12384139 |doi=
*cite journal | author=de Rooij J, Zwartkruis FJ, Verheijen MH, "et al." |title=Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. |journal=Nature |volume=396 |issue= 6710 |pages= 474–7 |year= 1998 |pmid= 9853756 |doi= 10.1038/24884
*cite journal | author=Kawasaki H, Springett GM, Mochizuki N, "et al." |title=A family of cAMP-binding proteins that directly activate Rap1. |journal=Science |volume=282 |issue= 5397 |pages= 2275–9 |year= 1999 |pmid= 9856955 |doi=
*cite journal | author=de Rooij J, Rehmann H, van Triest M, "et al." |title=Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs. |journal=J. Biol. Chem. |volume=275 |issue= 27 |pages= 20829–36 |year= 2000 |pmid= 10777494 |doi= 10.1074/jbc.M001113200
*cite journal | author=Mei FC, Qiao J, Tsygankova OM, "et al." |title=Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation. |journal=J. Biol. Chem. |volume=277 |issue= 13 |pages= 11497–504 |year= 2002 |pmid= 11801596 |doi= 10.1074/jbc.M110856200
*cite journal | author=Qiao J, Mei FC, Popov VL, "et al." |title=Cell cycle-dependent subcellular localization of exchange factor directly activated by cAMP. |journal=J. Biol. Chem. |volume=277 |issue= 29 |pages= 26581–6 |year= 2002 |pmid= 12000763 |doi= 10.1074/jbc.M203571200
*cite journal | author=Rehmann H, Prakash B, Wolf E, "et al." |title=Structure and regulation of the cAMP-binding domains of Epac2. |journal=Nat. Struct. Biol. |volume=10 |issue= 1 |pages= 26–32 |year= 2007 |pmid= 12469113 |doi= 10.1038/nsb878
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ohba Y, Kurokawa K, Matsuda M |title=Mechanism of the spatio-temporal regulation of Ras and Rap1. |journal=EMBO J. |volume=22 |issue= 4 |pages= 859–69 |year= 2003 |pmid= 12574122 |doi= 10.1093/emboj/cdg087
*cite journal | author=Rehmann H, Rueppel A, Bos JL, Wittinghofer A |title=Communication between the regulatory and the catalytic region of the cAMP-responsive guanine nucleotide exchange factor Epac. |journal=J. Biol. Chem. |volume=278 |issue= 26 |pages= 23508–14 |year= 2003 |pmid= 12707263 |doi= 10.1074/jbc.M301680200
*cite journal | author=Hochbaum D, Tanos T, Ribeiro-Neto F, "et al." |title=Activation of JNK by Epac is independent of its activity as a Rap guanine nucleotide exchanger. |journal=J. Biol. Chem. |volume=278 |issue= 36 |pages= 33738–46 |year= 2003 |pmid= 12783872 |doi= 10.1074/jbc.M305208200
*cite journal | author=Tiwari S, Felekkis K, Moon EY, "et al." |title=Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis. |journal=Blood |volume=103 |issue= 7 |pages= 2661–7 |year= 2004 |pmid= 14615375 |doi= 10.1182/blood-2003-06-2154
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Brandenberger R, Wei H, Zhang S, "et al." |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971
*cite journal | author=Magiera MM, Gupta M, Rundell CJ, "et al." |title=Exchange protein directly activated by cAMP (EPAC) interacts with the light chain (LC) 2 of MAP1A. |journal=Biochem. J. |volume=382 |issue= Pt 3 |pages= 803–10 |year= 2005 |pmid= 15202935 |doi= 10.1042/BJ20040122
*cite journal | author=Enserink JM, Price LS, Methi T, "et al." |title=The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin. |journal=J. Biol. Chem. |volume=279 |issue= 43 |pages= 44889–96 |year= 2004 |pmid= 15302884 |doi= 10.1074/jbc.M404599200
*cite journal | author=Keiper M, Stope MB, Szatkowski D, "et al." |title=Epac- and Ca2+ -controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors. |journal=J. Biol. Chem. |volume=279 |issue= 45 |pages= 46497–508 |year= 2004 |pmid= 15319437 |doi= 10.1074/jbc.M403604200
*cite journal | author=Cullere X, Shaw SK, Andersson L, "et al." |title=Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase. |journal=Blood |volume=105 |issue= 5 |pages= 1950–5 |year= 2005 |pmid= 15374886 |doi= 10.1182/blood-2004-05-1987
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504PBB_Controls
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