LAMP2

Lysosomal-associated membrane protein 2 (LAMP2") also known as CD107b (Cluster of D"'ifferentiation 107b), is a human gene.

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of the gene produces two known products of unknown function.cite web | title = Entrez Gene: LAMP2 lysosomal-associated membrane protein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3920| accessdate = ]

ee also

* Cluster of differentiation

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Chang MH, Karageorgos LE, Meikle PJ |title=CD107a (LAMP-1) and CD107b (LAMP-2). |journal=J. Biol. Regul. Homeost. Agents |volume=16 |issue= 2 |pages= 147–51 |year= 2003 |pmid= 12144129 |doi=
*cite journal | author=Schleutker J, Haataja L, Renlund M, "et al." |title=Confirmation of the chromosomal localization of human lamp genes and their exclusion as candidate genes for Salla disease. |journal=Hum. Genet. |volume=88 |issue= 1 |pages= 95–7 |year= 1992 |pmid= 1959930 |doi=
*cite journal | author=Manoni M, Tribioli C, Lazzari B, "et al." |title=The nucleotide sequence of a CpG island demonstrates the presence of the first exon of the gene encoding the human lysosomal membrane protein lamp2 and assigns the gene to Xq24. |journal=Genomics |volume=9 |issue= 3 |pages= 551–4 |year= 1991 |pmid= 2032724 |doi=
*cite journal | author=Carlsson SR, Fukuda M |title=The polylactosaminoglycans of human lysosomal membrane glycoproteins lamp-1 and lamp-2. Localization on the peptide backbones. |journal=J. Biol. Chem. |volume=265 |issue= 33 |pages= 20488–95 |year= 1990 |pmid= 2243102 |doi=
*cite journal | author=Mattei MG, Matterson J, Chen JW, "et al." |title=Two human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2, are encoded by genes localized to chromosome 13q34 and chromosome Xq24-25, respectively. |journal=J. Biol. Chem. |volume=265 |issue= 13 |pages= 7548–51 |year= 1990 |pmid= 2332441 |doi=
*cite journal | author=Mane SM, Marzella L, Bainton DF, "et al." |title=Purification and characterization of human lysosomal membrane glycoproteins. |journal=Arch. Biochem. Biophys. |volume=268 |issue= 1 |pages= 360–78 |year= 1989 |pmid= 2912382 |doi=
*cite journal | author=Fukuda M, Viitala J, Matteson J, Carlsson SR |title=Cloning of cDNAs encoding human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Comparison of their deduced amino acid sequences. |journal=J. Biol. Chem. |volume=263 |issue= 35 |pages= 18920–8 |year= 1989 |pmid= 3198605 |doi=
*cite journal | author=Dahlgren C, Carlsson SR, Karlsson A, "et al." |title=The lysosomal membrane glycoproteins Lamp-1 and Lamp-2 are present in mobilizable organelles, but are absent from the azurophil granules of human neutrophils. |journal=Biochem. J. |volume=311 ( Pt 2) |issue= |pages= 667–74 |year= 1995 |pmid= 7487911 |doi=
*cite journal | author=Konecki DS, Foetisch K, Zimmer KP, "et al." |title=An alternatively spliced form of the human lysosome-associated membrane protein-2 gene is expressed in a tissue-specific manner. |journal=Biochem. Biophys. Res. Commun. |volume=215 |issue= 2 |pages= 757–67 |year= 1995 |pmid= 7488019 |doi=
*cite journal | author=Konecki DS, Foetisch K, Schlotter M, Lichter-Konecki U |title=Complete cDNA sequence of human lysosome-associated membrane protein-2. |journal=Biochem. Biophys. Res. Commun. |volume=205 |issue= 1 |pages= 1–5 |year= 1995 |pmid= 7999007 |doi=
*cite journal | author=Carlsson SR, Lycksell PO, Fukuda M |title=Assignment of O-glycan attachment sites to the hinge-like regions of human lysosomal membrane glycoproteins lamp-1 and lamp-2. |journal=Arch. Biochem. Biophys. |volume=304 |issue= 1 |pages= 65–73 |year= 1993 |pmid= 8323299 |doi= 10.1006/abbi.1993.1322
*cite journal | author=Sawada R, Jardine KA, Fukuda M |title=The genes of major lysosomal membrane glycoproteins, lamp-1 and lamp-2. 5'-flanking sequence of lamp-2 gene and comparison of exon organization in two genes. |journal=J. Biol. Chem. |volume=268 |issue= 12 |pages= 9014–22 |year= 1993 |pmid= 8517882 |doi=
*cite journal | author=Kannan K, Stewart RM, Bounds W, "et al." |title=Lysosome-associated membrane proteins h-LAMP1 (CD107a) and h-LAMP2 (CD107b) are activation-dependent cell surface glycoproteins in human peripheral blood mononuclear cells which mediate cell adhesion to vascular endothelium. |journal=Cell. Immunol. |volume=171 |issue= 1 |pages= 10–9 |year= 1996 |pmid= 8660832 |doi= 10.1006/cimm.1996.0167
*cite journal | author=Israels SJ, McMillan EM, Robertson C, "et al." |title=The lysosomal granule membrane protein, LAMP-2, is also present in platelet dense granule membranes. |journal=Thromb. Haemost. |volume=75 |issue= 4 |pages= 623–9 |year= 1996 |pmid= 8743190 |doi=
*cite journal | author=Aumüller G, Renneberg H, Hasilik A |title=Distribution and subcellular localization of a lysosome-associated protein in human genital organs. |journal=Cell Tissue Res. |volume=287 |issue= 2 |pages= 335–42 |year= 1997 |pmid= 8995204 |doi=
*cite journal | author=Akasaki K, Michihara A, Fujiwara Y, "et al." |title=Biosynthetic transport of a major lysosome-associated membrane glycoprotein 2, lamp-2: a significant fraction of newly synthesized lamp-2 is delivered to lysosomes by way of early endosomes. |journal=J. Biochem. |volume=120 |issue= 6 |pages= 1088–94 |year= 1997 |pmid= 9010755 |doi=
*cite journal | author=Karlsson K, Carlsson SR |title=Sorting of lysosomal membrane glycoproteins lamp-1 and lamp-2 into vesicles distinct from mannose 6-phosphate receptor/gamma-adaptin vesicles at the trans-Golgi network. |journal=J. Biol. Chem. |volume=273 |issue= 30 |pages= 18966–73 |year= 1998 |pmid= 9668075 |doi=
*cite journal | author=Ayala P, Lin L, Hopper S, "et al." |title=Infection of epithelial cells by pathogenic neisseriae reduces the levels of multiple lysosomal constituents. |journal=Infect. Immun. |volume=66 |issue= 10 |pages= 5001–7 |year= 1998 |pmid= 9746610 |doi=
*cite journal | author=Furuta K, Yang XL, Chen JS, "et al." |title=Differential expression of the lysosome-associated membrane proteins in normal human tissues. |journal=Arch. Biochem. Biophys. |volume=365 |issue= 1 |pages= 75–82 |year= 1999 |pmid= 10222041 |doi= 10.1006/abbi.1999.1147
*cite journal | author=Nishino I, Fu J, Tanji K, "et al." |title=Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). |journal=Nature |volume=406 |issue= 6798 |pages= 906–10 |year= 2000 |pmid= 10972294 |doi= 10.1038/35022604

External links

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