S100A7

S100 calcium binding protein A7, also known as S100A7, is a human gene.

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known.cite web | title = Entrez Gene: S100A7 S100 calcium binding protein A7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6278| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Schäfer BW, Heizmann CW |title=The S100 family of EF-hand calcium-binding proteins: functions and pathology. |journal=Trends Biochem. Sci. |volume=21 |issue= 4 |pages= 134–40 |year= 1996 |pmid= 8701470 |doi=
*cite journal | author=Watson PH, Leygue ER, Murphy LC |title=Psoriasin (S100A7). |journal=Int. J. Biochem. Cell Biol. |volume=30 |issue= 5 |pages= 567–71 |year= 1998 |pmid= 9693957 |doi=
*cite journal | author=Rasmussen HH, van Damme J, Puype M, "et al." |title=Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. |journal=Electrophoresis |volume=13 |issue= 12 |pages= 960–9 |year= 1993 |pmid= 1286667 |doi=
*cite journal | author=Madsen P, Rasmussen HH, Leffers H, "et al." |title=Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin. |journal=J. Invest. Dermatol. |volume=97 |issue= 4 |pages= 701–12 |year= 1991 |pmid= 1940442 |doi=
*cite journal | author=Schäfer BW, Wicki R, Engelkamp D, "et al." |title=Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family. |journal=Genomics |volume=25 |issue= 3 |pages= 638–43 |year= 1995 |pmid= 7759097 |doi=
*cite journal | author=Hoffmann HJ, Olsen E, Etzerodt M, "et al." |title=Psoriasin binds calcium and is upregulated by calcium to levels that resemble those observed in normal skin. |journal=J. Invest. Dermatol. |volume=103 |issue= 3 |pages= 370–5 |year= 1994 |pmid= 8077703 |doi=
*cite journal | author=Bürgisser DM, Siegenthaler G, Kuster T, "et al." |title=Amino acid sequence analysis of human S100A7 (psoriasin) by tandem mass spectrometry. |journal=Biochem. Biophys. Res. Commun. |volume=217 |issue= 1 |pages= 257–63 |year= 1996 |pmid= 8526920 |doi= 10.1006/bbrc.1995.2772
*cite journal | author=Celis JE, Rasmussen HH, Vorum H, "et al." |title=Bladder squamous cell carcinomas express psoriasin and externalize it to the urine. |journal=J. Urol. |volume=155 |issue= 6 |pages= 2105–12 |year= 1996 |pmid= 8618345 |doi=
*cite journal | author=Brodersen DE, Etzerodt M, Madsen P, "et al." |title=EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing. |journal=Structure |volume=6 |issue= 4 |pages= 477–89 |year= 1998 |pmid= 9562557 |doi=
*cite journal | author=Brodersen DE, Nyborg J, Kjeldgaard M |title=Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loaded and Zn2+-free states. |journal=Biochemistry |volume=38 |issue= 6 |pages= 1695–704 |year= 1999 |pmid= 10026247 |doi= 10.1021/bi982483d
*cite journal | author=Semprini S, Capon F, Bovolenta S, "et al." |title=Genomic structure, promoter characterisation and mutational analysis of the S100A7 gene: exclusion of a candidate for familial psoriasis susceptibility. |journal=Hum. Genet. |volume=104 |issue= 2 |pages= 130–4 |year= 1999 |pmid= 10190323 |doi=
*cite journal | author=Hagens G, Masouyé I, Augsburger E, "et al." |title=Calcium-binding protein S100A7 and epidermal-type fatty acid-binding protein are associated in the cytosol of human keratinocytes. |journal=Biochem. J. |volume=339 ( Pt 2) |issue= |pages= 419–27 |year= 1999 |pmid= 10191275 |doi=
*cite journal | author=Hagens G, Roulin K, Hotz R, "et al." |title=Probable interaction between S100A7 and E-FABP in the cytosol of human keratinocytes from psoriatic scales. |journal=Mol. Cell. Biochem. |volume=192 |issue= 1-2 |pages= 123–8 |year= 1999 |pmid= 10331666 |doi=
*cite journal | author=Al-Haddad S, Zhang Z, Leygue E, "et al." |title=Psoriasin (S100A7) expression and invasive breast cancer. |journal=Am. J. Pathol. |volume=155 |issue= 6 |pages= 2057–66 |year= 1999 |pmid= 10595935 |doi=
*cite journal | author=Dias Neto E, Correa RG, Verjovski-Almeida S, "et al." |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491–6 |year= 2000 |pmid= 10737800 |doi=
*cite journal | author=Ruse M, Lambert A, Robinson N, "et al." |title=S100A7, S100A10, and S100A11 are transglutaminase substrates. |journal=Biochemistry |volume=40 |issue= 10 |pages= 3167–73 |year= 2001 |pmid= 11258932 |doi=
*cite journal | author=Enerbäck C, Porter DA, Seth P, "et al." |title=Psoriasin expression in mammary epithelial cells in vitro and in vivo. |journal=Cancer Res. |volume=62 |issue= 1 |pages= 43–7 |year= 2002 |pmid= 11782356 |doi=
*cite journal | author=Gemmill RM, Bemis LT, Lee JP, "et al." |title=The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway. |journal=Oncogene |volume=21 |issue= 22 |pages= 3507–16 |year= 2002 |pmid= 12032852 |doi= 10.1038/sj.onc.1205437

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