TOP1

TOP1

Topoisomerase (DNA) I, also known as TOP1, is a human gene.

PBB_Summary
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summary_text = This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [cite web | title = Entrez Gene: TOP1 topoisomerase (DNA) I| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7150| accessdate = ]

ee also

* Type I topoisomerase
* Topoisomerase

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Friedberg EC |title=Relationships between DNA repair and transcription. |journal=Annu. Rev. Biochem. |volume=65 |issue= |pages= 15–42 |year= 1996 |pmid= 8811173 |doi= 10.1146/annurev.bi.65.070196.000311
*cite journal | author=Leppard JB, Champoux JJ |title=Human DNA topoisomerase I: relaxation, roles, and damage control. |journal=Chromosoma |volume=114 |issue= 2 |pages= 75–85 |year= 2005 |pmid= 15830206 |doi= 10.1007/s00412-005-0345-5

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Look at other dictionaries:

  • top — TOP1, topuri, s.n. 1. Pachet de hârtie sau de carton (cuprinzând un anumit număr de coli). 2. (pop.) Pachet de bumbac (cu un anumit număr de legături). 3. (înv.) Val de postav. – Din tc. top. Trimis de RACAI, 07.12.2003. Sursa: DEX 98  TOP2,… …   Dicționar Român

  • top — top1 /top/, n., adj., v., topped, topping. n. 1. the highest or loftiest point or part of anything; apex; summit. 2. the uppermost or upper part, surface, etc., of anything. 3. the higher end of anything on a slope. 4. Brit. a. a part considered… …   Universalium

  • top — top1 W2S1 [tɔp US ta:p] n ▬▬▬▬▬▬▬ 1¦(highest part)¦ 2¦(upper surface)¦ 3¦(best position)¦ 4¦(cover)¦ 5¦(clothes)¦ 6 be (at the) top of the list/agenda 7 on top 8 on top of something 9 one on top of the other …   Dictionary of contemporary English

  • top — top1 [ tap ] noun *** ▸ 1 highest place/part ▸ 2 highest/best position ▸ 3 container lid/cover ▸ 4 piece of clothing ▸ 5 farthest part ▸ 6 toy that spins ▸ 7 fruit/vegetable leaves ▸ 8 beginning ▸ + PHRASES 1. ) count usually singular the highest …   Usage of the words and phrases in modern English

  • top — top1 noun 1》 the highest or uppermost point, part, or surface.     ↘the leaves, stems, and shoots of a plant, especially those of a vegetable grown for its root. 2》 a thing or part placed on or fitted to the upper part of something.     ↘a… …   English new terms dictionary

  • top — tȍp1 [b] (I)[/b] prid. <indekl.> DEFINICIJA razg. nesamostalna riječ koja se piše s drugim riječima onako kako se one pišu u zn. najbolji, najkvalitetniji, vrhunski SINTAGMA top down (izg. top dȃun) postupak ekon. pristup oblikovanju… …   Hrvatski jezični portal

  • top — tȍp1 [b] (II)[/b] ž DEFINICIJA žarg. ženska bluza (ob. majica) bez rukava koja se nosi tako da se vidi ispod druge, gornje bluze (nekad se nosi i samostalno kao jedini gornji dio ženske odjeće) …   Hrvatski jezični portal

  • top — top1 (Del ingl. to stop, parar, detener). interj. Mar. U. para ordenar que pare una maniobra. top2 (Del ingl. top). m. Prenda de vestir femenina, generalmente ajustada, que cubre el pecho y llega como mucho hasta la cintura …   Diccionario de la lengua española

  • History of Pakistan — also see History of AJK · Balochistan · G B · KPK · Punjab · Sindh Timeline of Pakistan …   Wikipedia

  • Paul Chalifoux — is a politician and the former mayor of St. Albert, Alberta, He has served two terms as mayor, first one having taken place from 1998 to 2001 and the second from 2004 to 2007.Chalifoux s first attempt at winning elected office was in the 1968… …   Wikipedia

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