SH3KBP1

SH3-domain kinase binding protein 1, also known as SH3KBP1, is a human gene.

PBB_Summary
section_title =
summary_text = CBL (MIM 165360) constitutively interacts with SH3 domain-containing proteins and, upon tyrosine phosphorylation, with SH2 domain-containing proteins. The SH3KBP1 gene encodes an 85-kD CBL-interacting protein that enhances tumor necrosis factor (MIM 191160)-mediated apoptotic cell death (Narita et al., 2001). [supplied by OMIM] cite web | title = Entrez Gene: SH3KBP1 SH3-domain kinase binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=30011| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Adams MD, Kerlavage AR, Fleischmann RD, "et al." |title=Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. |journal=Nature |volume=377 |issue= 6547 Suppl |pages= 3–174 |year= 1995 |pmid= 7566098 |doi=
*cite journal | author=Hillier LD, Lennon G, Becker M, "et al." |title=Generation and analysis of 280,000 human expressed sequence tags. |journal=Genome Res. |volume=6 |issue= 9 |pages= 807–28 |year= 1997 |pmid= 8889549 |doi=
*cite journal | author=Salvatore P, Hanash CR, Kido Y, "et al." |title=Identification of sirm, a novel insulin-regulated SH3 binding protein that associates with Grb-2 and FYN. |journal=J. Biol. Chem. |volume=273 |issue= 12 |pages= 6989–97 |year= 1998 |pmid= 9507006 |doi=
*cite journal | author=Li J, Nishizawa K, An W, "et al." |title=A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion. |journal=EMBO J. |volume=17 |issue= 24 |pages= 7320–36 |year= 1999 |pmid= 9857189 |doi= 10.1093/emboj/17.24.7320
*cite journal | author=Take H, Watanabe S, Takeda K, "et al." |title=Cloning and characterization of a novel adaptor protein, CIN85, that interacts with c-Cbl. |journal=Biochem. Biophys. Res. Commun. |volume=268 |issue= 2 |pages= 321–8 |year= 2000 |pmid= 10679202 |doi= 10.1006/bbrc.2000.2147
*cite journal | author=Chen B, Borinstein SC, Gillis J, "et al." |title=The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes. |journal=J. Biol. Chem. |volume=275 |issue= 25 |pages= 19275–81 |year= 2000 |pmid= 10858458 |doi= 10.1074/jbc.M908994199
*cite journal | author=Gout I, Middleton G, Adu J, "et al." |title=Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein. |journal=EMBO J. |volume=19 |issue= 15 |pages= 4015–25 |year= 2000 |pmid= 10921882 |doi= 10.1093/emboj/19.15.4015
*cite journal | author=Watanabe S, Take H, Takeda K, "et al." |title=Characterization of the CIN85 adaptor protein and identification of components involved in CIN85 complexes. |journal=Biochem. Biophys. Res. Commun. |volume=278 |issue= 1 |pages= 167–74 |year= 2001 |pmid= 11071869 |doi= 10.1006/bbrc.2000.3760
*cite journal | author=Borinstein SC, Hyatt MA, Sykes VW, "et al." |title=SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins. |journal=Cell. Signal. |volume=12 |issue= 11-12 |pages= 769–79 |year= 2001 |pmid= 11152963 |doi=
*cite journal | author=Narita T, Amano F, Yoshizaki K, "et al." |title=Assignment of SH3KBP1 to human chromosome band Xp22.1-->p21.3 by in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=93 |issue= 1-2 |pages= 133–4 |year= 2001 |pmid= 11474197 |doi=
*cite journal | author=Soubeyran P, Kowanetz K, Szymkiewicz I, "et al." |title=Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. |journal=Nature |volume=416 |issue= 6877 |pages= 183–7 |year= 2002 |pmid= 11894095 |doi= 10.1038/416183a
*cite journal | author=Petrelli A, Gilestro GF, Lanzardo S, "et al." |title=The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met. |journal=Nature |volume=416 |issue= 6877 |pages= 187–90 |year= 2002 |pmid= 11894096 |doi= 10.1038/416187a
*cite journal | author=Scott MP, Zappacosta F, Kim EY, "et al." |title=Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1. |journal=J. Biol. Chem. |volume=277 |issue= 31 |pages= 28238–46 |year= 2002 |pmid= 12029088 |doi= 10.1074/jbc.M202783200
*cite journal | author=Verdier F, Valovka T, Zhyvoloup A, "et al." |title=Ruk is ubiquitinated but not degraded by the proteasome. |journal=Eur. J. Biochem. |volume=269 |issue= 14 |pages= 3402–8 |year= 2002 |pmid= 12135478 |doi=
*cite journal | author=Szymkiewicz I, Kowanetz K, Soubeyran P, "et al." |title=CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases. |journal=J. Biol. Chem. |volume=277 |issue= 42 |pages= 39666–72 |year= 2002 |pmid= 12177062 |doi= 10.1074/jbc.M205535200
*cite journal | author=Haglund K, Shimokawa N, Szymkiewicz I, Dikic I |title=Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 19 |pages= 12191–6 |year= 2002 |pmid= 12218189 |doi= 10.1073/pnas.192462299
*cite journal | author=Buchman VL, Luke C, Borthwick EB, "et al." |title=Organization of the mouse Ruk locus and expression of isoforms in mouse tissues. |journal=Gene |volume=295 |issue= 1 |pages= 13–17 |year= 2003 |pmid= 12242006 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Tibaldi EV, Reinherz EL |title=CD2BP3, CIN85 and the structurally related adaptor protein CMS bind to the same CD2 cytoplasmic segment, but elicit divergent functional activities. |journal=Int. Immunol. |volume=15 |issue= 3 |pages= 313–29 |year= 2003 |pmid= 12618476 |doi=
*cite journal | author=Hutchings NJ, Clarkson N, Chalkley R, "et al." |title=Linking the T cell surface protein CD2 to the actin-capping protein CAPZ via CMS and CIN85. |journal=J. Biol. Chem. |volume=278 |issue= 25 |pages= 22396–403 |year= 2003 |pmid= 12690097 |doi= 10.1074/jbc.M302540200

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