Arsenate reductase (glutaredoxin)

In enzymology, an arsenate reductase (glutaredoxin) (EC number|1.20.4.1) is an enzyme that catalyzes the chemical reaction

:arsenate + glutaredoxin $ightleftharpoons$ arsenite + glutaredoxin disulfide + H₂O

Thus, the two substrates of this enzyme are arsenate and glutaredoxin, whereas its 3 products are arsenite, glutaredoxin disulfide, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on phosphorus or arsenic in donor with disulfide as acceptor. The systematic name of this enzyme class is glutharedoxin:arsenate oxidoreductase.

tructural studies

As of late 2007, 12 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1RXE, PDB link|1RXI, PDB link|1S3C, PDB link|1S3D, PDB link|1SD8, PDB link|1SD9, PDB link|1SJZ, PDB link|1SK0, PDB link|1SK1, PDB link|1SK2, PDB link|1Z2D, and PDB link|1Z2E.

References

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External links

Gene Ontology (GO) codes