Lactate-malate transhydrogenase

Lactate-malate transhydrogenase

In enzymology, a lactate---malate transhydrogenase (EC number|1.1.99.7) is an enzyme that catalyzes the chemical reaction

:(S)-lactate + oxaloacetate ightleftharpoons pyruvate + malate

Thus, the two substrates of this enzyme are (S)-lactate and oxaloacetate, whereas its two products are pyruvate and malate.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is (S)-lactate:oxaloacetate oxidoreductase. This enzyme is also called malate-lactate transhydrogenase. This enzyme participates in pyruvate metabolism. It employs one cofactor, nicotinamide D-ribonucleotide.

References

*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|9077-15-0."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

  • metabolism — /meuh tab euh liz euhm/, n. 1. Biol., Physiol. the sum of the physical and chemical processes in an organism by which its material substance is produced, maintained, and destroyed, and by which energy is made available. Cf. anabolism, catabolism …   Universalium

  • MITOCHONDRIES — Vers 1890, Altman découvre dans les cellules des granules très semblables en dimensions et aspects à des bactéries. Il leur donne le nom de bioblastes. En 1897, le terme de mitochondries est introduit par Benda pour désigner ces éléments. On… …   Encyclopédie Universelle

  • Oxidoreductase — In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule (the reductant, also called the hydrogen or electron donor) to another (the oxidant, also called the hydrogen or electron acceptor). This… …   Wikipedia

  • Multilocus sequence typing — (MLST) is a technique in molecular biology for the typing of multiple loci. The procedure characterizes isolates of bacterial species using the DNA sequences of internal fragments of multiple housekeeping genes. Approximately 450 500 bp internal… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”