Plasmanylethanolamine desaturase

In enzymology, a plasmanylethanolamine desaturase (EC number|1.14.99.19) is an enzyme that catalyzes the chemical reaction

:O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + AH₂ + O₂ $ightleftharpoons$ O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + A + 2 H₂O

The 3 substrates of this enzyme are O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine, AH2, and O₂, whereas its 3 products are O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine, A, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine,hydrogen-donor:oxy gen oxidoreductase. Other names in common use include alkylacylglycerophosphoethanolamine desaturase, alkylacylglycero-phosphorylethanolamine dehydrogenase, dehydrogenase, alkyl-acylglycerophosphorylethanolamine, 1-O-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine desaturase, and 1-O-alkyl 2-acyl-sn-glycero-3-phosphorylethanolamine desaturase. This enzyme participates in ether lipid metabolism. It has 3 cofactors: ATP, Manganese, and Magnesium.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|39391-13-4."

Gene Ontology (GO) codes