- Linoleoyl-CoA desaturase
In
enzymology , a linoleoyl-CoA desaturase (EC number|1.14.19.3) is anenzyme that catalyzes thechemical reaction :linoleoyl-CoA + AH2 + O2 gamma-linolenoyl-CoA + A + 2 H2O
The 3 substrates of this enzyme are
linoleoyl-CoA ,AH2 , and O2, whereas its 3 products aregamma-linolenoyl-CoA ,A , and H2O.This enzyme belongs to the family of
oxidoreductase s, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with oxidation of a pair of donors resulting in the reduction of O to two molecules of water. The systematic name of this enzyme class is linoleoyl-CoA,hydrogen-donor:oxygen oxidoreductase. Other names in common use include Delta6-desaturase, Delta6-fatty acyl-CoA desaturase, Delta6-acyl CoA desaturase, fatty acid Delta6-desaturase, fatty acid 6-desaturase, linoleate desaturase, linoleic desaturase, linoleic acid desaturase, linoleoyl CoA desaturase, linoleoyl-coenzyme A desaturase, and long-chain fatty acid Delta6-desaturase. This enzyme participates inlinoleic acid metabolism . It employs one cofactor,iron .References
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External links
::"The
CAS registry number for this enzyme class is CAS registry|9014-34-0."Gene Ontology (GO) codes
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