Leucocyanidin oxygenase

In enzymology, a leucocyanidin oxygenase (EC number|1.14.11.19) is an enzyme that catalyzes the chemical reaction

:leucocyanidin + 2-oxoglutarate + O₂ $ightleftharpoons$ cis- and trans-dihydroquercetins + succinate + CO₂ + 2 H₂O

The 3 substrates of this enzyme are leucocyanidin, 2-oxoglutarate, and O₂, whereas its 5 products are cis-dihydroquercetin, trans-dihydroquercetin, succinate, CO₂, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with 2-oxoglutarate as one donor, and incorporation of one atom o oxygen into each donor. The systematic name of this enzyme class is leucocyanidin,2-oxoglutarate:oxygen oxidoreductase. This enzyme is also called anthocyanidin synthase. This enzyme participates in flavonoid biosynthesis.

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|2BRT.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|180984-01-4."

Gene Ontology (GO) codes