2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

In enzymology, a 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC number|1.3.1.28) is an enzyme that catalyzes the chemical reaction

:2,3-dihydro-2,3-dihydroxybenzoate + NAD⁺ $ightleftharpoons$ 2,3-dihydroxybenzoate + NADH + H⁺

Thus, the two substrates of this enzyme are 2,3-dihydro-2,3-dihydroxybenzoate and NAD⁺, whereas its 3 products are 2,3-dihydroxybenzoate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase. This enzyme is also called 2,3-DHB dehydrogenase. This enzyme participates in biosynthesis of siderophore group nonribosomal and .

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|2FWM.

References

*

External links

::"The CAS registry number for this enzyme class is CAS registry|37250-40-1."

Gene Ontology (GO) codes