RRNA (guanine-N1-)-methyltransferase

In enzymology, a rRNA (guanine-N1-)-methyltransferase (EC number|2.1.1.51) is an enzyme that catalyzes the chemical reaction

:S-adenosyl-L-methionine + rRNA $ightleftharpoons$ S-adenosyl-L-homocysteine + rRNA containing N₁-methylguanine

Thus, the two substrates of this enzyme are S-adenosyl methionine and rRNA, whereas its two products are S-adenosylhomocysteine and rRNA containing N1-methylguanine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:rRNA (guanine-N1-)-methyltransferase. Other names in common use include ribosomal ribonucleate guanine 1-methyltransferase, and S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase.

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|1P91.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|50812-25-4."

Gene Ontology (GO) codes