(ribulose-bisphosphate carboxylase)-lysine N-methyltransferase

In enzymology, a [ribulose-bisphosphate carboxylase] -lysine N-methyltransferase (EC number|2.1.1.127) is an enzyme that catalyzes the chemical reaction

:S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase] -lysine $ightleftharpoons$ S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase] -N₆-methyl-L-lysine

Thus, the two substrates of this enzyme are S-adenosyl methionine and [ribulose-1,5-bisphosphate carboxylase-lysine] , whereas its two products are S-adenosylhomocysteine and [ribulose-1,5-bisphosphate carboxylase-N6-methyl-L-lysine] .

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine: [3-phospho-D-glycerate-carboxy-lyase (dimerizing)] -lysine N6-methyltransferase. Other names in common use include rubisco methyltransferase, ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase, ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit, epsilonN-methyltransferase, S-adenosyl-L-methionine: [3-phospho-D-glycerate-carboxy-lyase, and (dimerizing)] -lysine 6-N-methyltransferase.

tructural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1MLV, PDB link|1OZV, PDB link|1P0Y, PDB link|2H21, PDB link|2H23, PDB link|2H2E, and PDB link|2H2J.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|139171-98-5."

Gene Ontology (GO) codes