Indolepyruvate C-methyltransferase

In enzymology, an indolepyruvate C-methyltransferase (EC number|2.1.1.47) is an enzyme that catalyzes the chemical reaction

:S-adenosyl-L-methionine + (indol-3-yl)pyruvate $ightleftharpoons$ S-adenosyl-L-homocysteine + (3S)-3-(indol-3-yl)-3-oxobutanoate

Thus, the two substrates of this enzyme are S-adenosyl methionine and (indol-3-yl)pyruvate, whereas its two products are S-adenosylhomocysteine and (3S)-3-(indol-3-yl)-3-oxobutanoate.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine: (indol-3-yl)pyruvate C-methyltransferase. Other names in common use include indolepyruvate methyltransferase, indolepyruvate 3-methyltransferase, indolepyruvic acid methyltransferase, and S-adenosyl-L-methionine:indolepyruvate C-methyltransferase. This enzyme participates in tryptophan metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|54576-88-4."

Gene Ontology (GO) codes