2-Methyl-3,3-diphenyl-3-propanolamine

Drugbox
IUPAC_name = 3-amino-2-methyl-1,1-di(phenyl)propan-1-ol


width= 150
CAS_number= 33887-05-7
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PubChem= 26538
DrugBank=
C=16 | H=19 | N=1 | O=1
molecular_weight = 241.33 g/mol
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legal_status = Legal
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2-MDP is a dissociative anaesthetic drug which has been found to be an NMDA antagonist and produces similar effects to PCP in animals. The "levo" or (-) isomer is the active form of the drug. [Tang AH, Cangelosi AA, Code RA, Franklin SR. Phencyclidine-like behavioral effects of 2-methyl-3,3-diphenyl-3-propanolamine (2-MDP)."Pharmacology, Biochemistry and Behaviour". 1984 Feb;20(2):209-13.] [Blake JC, Davies SN, Church J, Martin D, Lodge D. 2-Methyl-3,3-diphenyl-3-propanolamine (2-MDP) selectively antagonises N-methyl-aspartate (NMA). "Pharmacology, Biochemistry and Behaviour". 1986 Jan;24(1):23-5.]

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