HLA-A25

SerotypeA_normal
locus = A
type = 25
allelegroup = 25
broad = 10 | sister1 = 66 | sister2 = 43 | sister3 = 34 | sister4 = 26
oneallele = 01
dominant = 01
alleles = 1
common_alleles = 1
alias = A10
nick1 = A25
allele1 = 01
mode = SW Asia to NW Europe
lead_comment = is believed to have been formed by a single gene conversion between another HLA-A and the A*2601 allele.cite journal | author = Madrigal JA, Hildebrand WH, Belich MP, "et al" | title = Structural diversity in the HLA-A10 family of alleles: correlations with serology | journal = Tissue Antigens | volume = 41 | issue = 2 | pages = 72–80 | year = 1993 | pmid = 8475492 | doi = ]
types =2
2ndType = 10
type1alle1freq = 95 |type2alle1freq = 2 |N1 = 1375
serotype_comment = reasonably good serotyping with no overt false recognition.

A25 frequencies

AlleleFreq
Placement = right
Allele = A*2501
Freq1 = 5.7 | People1 = Saudi Arabia
Freq2 = 5.1 | People2 = India Jalpaiguri Toto
Freq3 = 5.1 | People3 = Russia Northwest
Freq4 = 4.8 | People4 = Serbia
Freq5 = 4.3 | People5 = Spain Pas Valley
Freq6 = 4.2 | People6 = Czech Republic
Freq7 = 4.2 | People7 = Spain North Cantabrian
Freq8 = 4.0 | People8 = Russia Arkhangelsk Pomors
Freq9 = 3.8 | People9 = Spain North Cabuernigo
Freq10 = 3.6 | People10 = Ireland South
Freq11 = 3.5 | People11 = Romanian
Freq12 = 3.4 | People12 = USA Caucasians (3)
Freq13 = 3.0 | People13 = Croatia
Freq14 = 2.7 | People14 = Bulgaria
Freq15 = 2.7 | People15 = Spain Basque Arratia Vall…
Freq16 = 2.5 | People16 = Sweden Uppsala County
Freq17 = 2.5 | People17 = Scotland Orkney
Freq18 = 2.4 | People18 = German Essen
Freq19 = 2.1 | People19 = Wales
Freq20 = 2.0 | People20 = Argentina Buenos Aires
Freq21 = 2.0 | People21 = Ireland Northern
Freq22 = 2.0 | People22 = Morocco
Freq23 = 2.0 | People23 = Spain Eastern Andalusia
Freq24 = 1.9 | People24 = Australia New South Wales
Freq25 = 1.9 | People25 = Georgia Svaneti Svans
Freq26 = 1.9 | People26 = Italy
Freq27 = 1.9 | People27 = Macedonia
Freq28 = 1.9 | People28 = Sweden Stockholm
Freq29 = 1.9 | People29 = England Liverpool
Freq30 = 1.8 | People30 = Azores Central Islands
Freq31 = 1.8 | People31 = Turkey
Freq32 = 1.8 | People32 = England Lancaster
Freq33 = 1.6 | People33 = England Sheffield
Freq34 = 1.5 | People34 = Israeli Jews
Freq35 = 1.5 | People35 = Spain Basque Gipuzkoa Pro…
Freq36 = 1.2 | People36 = Italy South Campania
Freq37 = 1.2 | People37 = New Caledonia
Freq38 = 1.2 | People38 = Uganda Kampala
Freq39 = 1.1 | People39 = Australia West
Freq40 = 1.1 | People40 = Finland
Freq41 = 1.1 | People41 = Portugal Centre (2)
Freq42 = 1.1 | People42 = Spain Catalonia Girona
Freq43 = 1.0 | People43 = Belguim
Freq44 = 1.0 | People44 = France Corsica
Freq45 = 1.0 | People45 = Mongolia Oold
Freq46 = 1.0 | People46 = Russia Murmansk Saomi
Freq47 = 0.9 | People47 = Russia Sakhalin Island Ni…
Freq48 = 0.8 | People48 = France South East
Freq49 = 0.8 | People49 = USA South Texas Hispanics
Freq50 = 0.7 | People50 = Morocco 'Berber' Nador Me…
Freq51 = 0.7 | People51 = USA South Dakota Lakota S…
Freq52 = 0.6 | People52 = Greece
Freq53 = 0.6 | People53 = USA Arizona Pima
Freq54 = 0.5 | People54 = Algeria1
Freq55 = 0.5 | People55 = China Qinghai Hui

A*2501 distribution is primarily located in Western Eurasia. Frequency tends to be highest in the populations that underwent later neolithization suggesting A*2501 spread in Europe. The high frequency in Saudi Arabia is suggestive of a source.

References