Lentinan

Drugbox
IUPAC_name = (2S,3R,4S,5S,6R)-2- [(2S,3R,4S,5R,6R)-2- [(2S,3R,4S,5R,6R)-2- [(2R,3R,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6- [(2R,3R,4S,5R,6R)-2,3,5-trihydroxy-6- [ [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] oxymethyl] oxan-4-yl] oxyoxan-4-yl] oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] oxy-3,5-dihydroxy-6- [ [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] oxymethyl] oxan-4-yl] oxy-6-(hydroxymethyl)oxane-3,4,5-triol

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CAS_number = 37339-90-5
ATC_prefix = L03
ATC_suffix = AX01
PubChem = 37723
DrugBank =
C=42|H=72|O=36
molecular_weight = 1152.99948 g/mol
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Lentinan is a form of beta-glucan, a strictly purified beta-1,6:beta-1,3-glucan. [http://cancerguide.org/cit_lentinan.html Cancer Guide] Includes many abstracts] It is an anti-tumor polysaccharide from the shiitake mushroom ("Lentinula edodes").

Lentinan is one of the host-mediated anti-cancer drugs which has been shown to affect host defense immune systems. [cite journal |author=Nakano H, Namatame K, Nemoto H, Motohashi H, Nishiyama K, Kumada K |title=A multi-institutional prospective study of lentinan in advanced gastric cancer patients with unresectable and recurrent diseases: effect on prolongation of survival and improvement of quality of life. Kanagawa Lentinan Research Group |journal=Hepatogastroenterology |volume=46 |issue=28 |pages=2662–8 |year=1999 |pmid=10522061 |doi=]

References

External links

* [http://www.drugs.com/npp/lentinan.html Lentinan] effects (antitumor and others)