Acoustic Radiation Force Impulse (ARFI) Imaging

Acoustic Radiation Force Impulse (ARFI) Imaging uses acoustic radiation force to generate images of the mechanical properties of soft tissue.

How it works

Acoustic radiation force is a phenomenon associated with the propagation of acoustic waves in attenuating media. Attenuation includes both scattering and absorption of the acoustic wave. Attenuation is a frequency dependent phenomenon, and in soft tissues it is dominated by absorption. With increasing acoustic frequencies, the tissue does not respond fast enough to the transitions between positive and negative pressures, thus its motion becomes out of phase with the acoustic wave, and energy is deposited into the tissue. This energy results in a momentum transfer in the direction of wave propagation and tissue heating. The momentum transfer generates a force causes displacement of the tissue, and the time scale of this response is much slower than that of the ultrasonic wave propagation. This interaction of sound with tissue can be used to derive additional information about the tissue, beyond what is normally provided in an ultrasonic image. The magnitude, location, spatial extent, and duration of acoustic radiation force can be controlled to interrogate the mechanical properties of the tissue.

Clinical applications

;Clinical applications of ARFI imaging include:
*Breast Mass Imaging
*Colorectal Tumor Imaging/Staging
*Liver Fibrosis Quantification
*Imaging RF ablation lesions
*Artery Characterization [Trahey, G.E. et al. "Acoustic Radiation Force Impulse Imaging of the Mechanical Properties of Arteries: In vivo and ex vivo results," UMB, 30(9), 1163-1171, 2004.]
*Cardiac Imaging
*Mechanical Finite Element Analysis
*Prostate Imaging
*Thermal Therapy

External links

* [http://kathynightingalelab.pratt.duke.edu Kathy Nightingale Lab Website]

References