Homoplasmy

Homoplasmy

Homoplasmy is the presence of a mutation affecting all of the mitochondrial DNA (mtDNA) copies in a cell. Since there are hundreds or even thousands of mtDNA copies in every eukaryotic cell, mutations may either be present in all copies (homoplasmy) or affect only a fraction of them (heteroplasmy).

See also microheteroplasmy.

Homeoplasmy = a state in which all the mitochondria of a cell or a tissue have the same genome, which may be either the wild type genome or a mutated one.

Homoplasmy may also refer to the presence of mutation, or insertion of a foreign gene, into all of the plant plastid organelles DNA e.g. all of the chloroplasts


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  • Homoplasmy — Ho mo*plas my, n. [Homo + Gr. ? anything formed, fr. ? to form, mold.] (Biol.) Resemblance between different plants or animals, in external shape, in general habit, or in organs, which is not due to descent from a common ancestor, but to similar… …   The Collaborative International Dictionary of English

  • homoplasmy — noun the presence of the same mutation in all copies of mitochondrial or plastid DNA within a single cell or individual Ant: heteroplasmy …   Wiktionary

  • homoplasmy — ho·mo·plas·my (hoґmo plaz″me) [homo + plasm] the presence of only a single type of mitochondrial or chloroplast DNA within a cell or individual …   Medical dictionary

  • homoplasmy — The condition in which all copies of an organelle in a cell are genetically identical. Opposite: heteroplasmy …   Glossary of Biotechnology

  • homoplasmy — homˈoplasmy / plaz mi/ or homopˈlasy noun The quality or fact of being homoplastic • • • Main Entry: ↑homo …   Useful english dictionary

  • Homogeny — Ho*mog e*ny, n. [Gr. ?; ? the same + ? race, kind.] 1. Joint nature. [Obs.] Bacon. [1913 Webster] 2. (Biol.) The correspondence of common descent; a term used to supersede homology by Lankester, who also used homoplasy to denote any superinduced… …   The Collaborative International Dictionary of English

  • Heteroplasmy — is the presence of a mixture of more than one type of an organellar genome (mitochondrial DNA (mtDNA) or plastid DNA) within a cell or individual. Since every eukaryotic cell contains many hundreds of mitochondria with hundreds of copies of mtDNA …   Wikipedia

  • List of genetics-related topics — This is a list of terms related to genetics. NOTOC # * 3 end * 5 end A * Acentric chromosome * Achondroplasia * Active site * Adam s Curse * Adaptation * Adenine * Adenosine * Adenovirus * Adenosine diphosphate (ADP) * Ala * Alagille syndrome *… …   Wikipedia

  • List of genetic engineering topics — NOTOC # 3 end 5 end A Acentric chromosome Achondroplasia Active site Adam s Curse Adaptation Adenine Adenosine Adenosine diphosphate Adenovirus ADP Ala Alagille syndrome Albino Alcoholism Alkylating agent Allele Allele frequency Alleles… …   Wikipedia

  • heteroplasmy — noun the presence of multiple kinds of mitochondrial or plastid DNA within a single cell or individual Ant: homoplasmy …   Wiktionary

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