Biobreeding rat

Biobreeding rat

Biobreeding rat also known as the BB rat is an inbred rat strain that spontaneously develops autoimmune Type 1 Diabetes. Like the NOD mice, BB rats are used as an animal model for Type 1 diabetes. The strain re-capitulates many of the features of human type 1 diabetes, and has contributed greatly to the research of T1D pathogenesis. [Mordes JP, Poussier P, Blankenhorn EP, Greiner DL: Rat models of type 1 diabetes: Genetics, environment and autoimmunity. Boca Raton, CRC Press, 2007]


Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Oncomouse — The OncoMouse or Harvard mouse is a type of laboratory mouse that has been genetically modified using modifications designed by Philip Leder and Timothy A Stewart[1] of Harvard University to carry a specific gene called an activated oncogene. The …   Wikipedia

  • Breeding — is the producing of offspring, usually animals or plants* Animal breeding, through selected specimens such as dogs, horses, and rabbits * Plant breeding, through selected specimens such as treesBreeding may also refer to:in science: * Biobreeding …   Wikipedia

  • NOD mice — Non obese diabetic or NOD mice, like the Biobreeding rat, are used as an animal model for type 1 diabetes.[1] Contents 1 History 2 Characteristics 3 Susceptibility …   Wikipedia

  • Diabetes (disambiguation) — Diabetes usually refers to diabetes mellitus, a group of metabolic diseases in which a person has high blood sugar. Contents 1 Diabetes mellitus 2 Diabetes insipidus …   Wikipedia

  • BB — bad breath; bed bath; beta blockade, beta blocker; biceps brachii; BioBreeding [rat]; blanket bath; blood bank; blood buffer; blow bottle; blue bloaters [emphysema]; bombesin; borderline; Bortfeld/Boyer [radiotherapy]; both bones; breakthrough… …   Medical dictionary

  • BB — • bad breath; • bed bath; • beta blockade, beta blocker; • biceps brachii; • BioBreeding [rat]; • blanket bath; • blood bank; • blood buffer; • blow bottle; • blue bloaters [emphysema]; • bombesin; • borderline; • Bortfeld/Boyer [radiotherapy]; • …   Dictionary of medical acronyms & abbreviations

  • BB/W — BioBreeding/Worcester [rat] …   Medical dictionary

  • BB/W — • BioBreeding/Worcester [rat] …   Dictionary of medical acronyms & abbreviations

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”