Signal recognition particle RNA

Signal recognition particle RNA

The signal recognition particle RNA is an RNA molecule that is a component of the signal recognition particle (SRP).

7SL RNA

In eukaryotes, the SRP RNA is known as 7SL RNA Although originally the SRP was thought to be only composed by 6 polypeptides, this small cytoplasmic RNA molecule was found to be a component of the complex.

The gene for 7SL is transcribed by the RNA polymerase III.

The common SINE family Alu probably originated from a duplication of a 7SL RNA gene.

4.5S RNA

References

* Walter P, Blobel G. "Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum.", Nature 21;299(5885):691-8 (1982).


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