Signal recognition particle RNA
- Signal recognition particle RNA
The signal recognition particle RNA is an RNA molecule that is a component of the signal recognition particle (SRP).
7SL RNA
In eukaryotes, the SRP RNA is known as 7SL RNA Although originally the SRP was thought to be only composed by 6 polypeptides, this small cytoplasmic RNA molecule was found to be a component of the complex.
The gene for 7SL is transcribed by the RNA polymerase III.
The common SINE family Alu probably originated from a duplication of a 7SL RNA gene.
4.5S RNA
References
* Walter P, Blobel G. "Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum.", Nature 21;299(5885):691-8 (1982).
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