Douglas Scott Falconer

Douglas Scott Falconer

Douglas Scott Falconer FRS FRSE (March 10, 1913, Oldmeldrum, Aberdeenshire – February 23, 2004, Edinburgh)[1] was a British geneticist known for his work in quantitative genetics.[2] Falconer's book Introduction to quantitative genetics was written in 1960 and became a valuable reference for generations of scientists. Its latest edition dates back to 1996 and is coauthored by Trudy F.C. Mackay.[3]

In 1951, Falconer described a novel mouse mutant that he called reeler for its peculiar gait.[4] Later research using these mice has led to the discovery of reelin, a protein playing important roles in corticogenesis, neuronal migration, and plasticity.

See also

References

  1. ^ Bowman, J. C. (2005). "Douglas Scott Falconer. 10 March 1913 - 23 February 2004: Elected F.R.S. 1973". Biographical Memoirs of Fellows of the Royal Society 51: 119. doi:10.1098/rsbm.2005.0008.  edit
  2. ^ MacKay, T. F. C. (2004). "Douglas Scott Falconer (1913–2004)". Heredity 93 (2): 119–121. doi:10.1038/sj.hdy.6800506. PMID 15241449.  edit
  3. ^ Hill, W. G.; MacKay, T. F. (2004). "D. S. Falconer and Introduction to quantitative genetics". Genetics 167 (4): 1529–1536. PMC 1471025. PMID 15342495. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1471025.  edit
  4. ^ Falconer, D. S. (1951). "Two new mutants, 'trembler' and 'reeler', with neurological actions in the house mouse (Mus musculus L.)". Journal of Genetics 50 (2): 192–205. doi:10.1007/BF02996215.  edit



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