Epipodophyllotoxin

Epipodophyllotoxin

Epipodophyllotoxins are alkaloids naturally occurring in the root of American Mayapple plant ("Podophyllum peltatum").

Some epipodophyllotoxin derivatives are currently used in the treatment of cancer. These include etoposide and teniposide. They act as anti-cancer drugs by inhibiting topoisomerase II.

ee also

*Podophyllotoxin


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  • epipodophyllotoxin — A substance being studied in the treatment of some types of cancer. Epipodophyllotoxin is extracted from the mandrake root Podophyllum peltatum. It is a type of topoisomerase inhibitor …   English dictionary of cancer terms

  • epipodophyllotoxin — Natural product that inhibits topoisomerase II. SEE ALSO: etoposide. [epi + Podophyllum, genus name of botanical source, + toxin] * * * epi·podo·phyl·lo·tox·in (ep″ĭ pod″o filґo tok″sin) [epi + podophyllotoxin] a chemical… …   Medical dictionary

  • List of oncology-related terms — This is a list of terms related to oncology. The original source for this list was the U.S. National Cancer Institute s public domain Dictionary of Cancer Terms . NOTOC 1 * 10 propargyl 10 deazaaminopterin * 12 O tetradecanoylphorbol 13 acetate * …   Wikipedia

  • History of cancer chemotherapy — The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs. Cancer drug development has exploded since then into a multi billion dollar industry. The targeted therapy revolution has… …   Wikipedia

  • Etoposide — drugbox IUPAC name = 4 demethyl epipodophyllotoxin 9 [4,6 O ( R ) ethylidene beta D glucopyranoside] , 4 (dihydrogen phosphate) CAS number = 33419 42 0 ATC prefix = L01 ATC suffix = CB01 ATC supplemental = PubChem = 36462 DrugBank = APRD00239 C …   Wikipedia

  • VP-16 — abbr. med. epipodophyllotoxin – эпидофиллотоксин …   Dictionary of English abbreviation

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