Tolonium chloride

Tolonium chloride

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ImageFile=Tolonium chloride.svg
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IUPACName=(7-amino-8-methyl- phenothiazin-3-ylidene)- dimethyl-ammonium
OtherNames=Toluidine blue O
Section1= Chembox Identifiers
CASNo=92-31-9
PubChem=7084
SMILES=CC1=CC2=C(C=C1N)SC3= CC(= [N+] (C)C)C=CC3=N2
MeSHName=Tolonium+chloride
Section2= Chembox Properties
Formula=C15H16N3S+
MolarMass=270.374 g/mol
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Section3= Chembox Hazards
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Tolonium chloride (INN, also known as toluidine blue O) is a compound used in histology.

Test for lignin

Toluidine blue solution is used in testing for lignin, a complex organic molecule that bonds to cellulose fibres and strengthens and hardens the cell walls in plants. A positive toluidine blue test causes the solution to turn from blue to blue-green. A similar test can be performed with phloroglucinol-HCl solution, which turns red.

Other Histological Uses

Toluidine Blue is often used to identify Mast cells. It is also used to stain proteoglycans and glycosaminoglycans in tissues such as cartilage.


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Look at other dictionaries:

  • tolonium chloride — noun Etymology: tolonium, New Latin, from tol + onium : toluidine blue for medicinal use …   Useful english dictionary

  • tolonium chloride — The medicinal grade of toluidine blue O, used as an antiheparin compound. * * * to·lo·ni·um chloride tə lō nē əm n TOLUIDINE BLUE * * * to·lo·ni·um chlo·ride (to loґne əm) an antiheparin compound that has been used in the treatment of… …   Medical dictionary

  • Toluidine — A chemical compound implicated, along with aniline, in the causation of bladder cancer. Aniline and o toluidine both compounds are aromatic amines are used in the manufacture of a variety of dyes, pharmaceuticals, pesticides, and chemicals… …   Medical dictionary

  • toluidine blue — n a basic thiazine dye that is related to methylene blue and is used as a biological stain and esp. formerly as an antihemorrhagic drug called also tolonium chloride * * * a dye used in microscopy for staining basophilic substances in tissue… …   Medical dictionary

  • toluidine blue O — n TOLUIDINE BLUE * * * a basic blue dye related to methylene blue; used for both orthochromatic and metachromatic staining. It is used for staining histologic sections, in the Nissl method of staining, as a nuclear counterstain, for staining… …   Medical dictionary

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