Riedel's thyroiditis

Infobox_Disease
Name = PAGENAME


Caption =
DiseasesDB = 11590
ICD10 = ICD10|E|06|5|e|00
ICD9 = ICD9|245.3
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj = med
eMedicineTopic = 2036
MeshID =

Riedel's thyroiditis, also called Riedel's struma is a chronic form of thyroiditis.

Pathophysiology

Riedel's thyroiditis is characterized by a replacement of the normal thyroid parenchyma by a dense fibrosis that invades adjacent structures of the neck and extends beyond the thyroid capsule.cite journal |author=Cho MH, Kim CS, Park JS, "et al" |title=Riedel's thyroiditis in a patient with recurrent subacute thyroiditis: a case report and review of the literature |journal=Endocr. J. |volume=54 |issue=4 |pages=559–62 |year=2007 |month=August |pmid=17603227 |doi= |url=http://joi.jlc.jst.go.jp/JST.JSTAGE/endocrj/K06-186?from=PubMed] This makes the thyroid gland stone-hard and fixed to adjacent structures.

A shared mechanism with retroperitoneal fibrosis and sclerosing cholangitis has been suggested.cite journal |author=De Boer WA |title=Riedel's thyroiditis, retroperitoneal fibrosis, and sclerosing cholangitis: diseases with one pathogenesis? |journal=Gut |volume=34 |issue=5 |pages=714 |year=1993 |month=May |pmid=8504980 |pmc=1374200 |doi= |url=http://gut.bmj.com/cgi/pmidlookup?view=long&pmid=8504980]

Prevalence

Riedel's thyroiditis is classified as rare. Most patients remain euthyroid, but approximately 30% of patients become hypothyroid and very few patients are hyperthyroid. It is most seen in women. [http://www.emedicine.com/med/topic2036.htm eMedicine] ]

Treatment

Tamoxifen has been proposed as part of a treatment plan.cite journal |author=Dabelic N, Jukic T, Labar Z, Novosel SA, Matesa N, Kusic Z |title=Riedel's thyroiditis treated with tamoxifen |journal=Croat. Med. J. |volume=44 |issue=2 |pages=239–41 |year=2003 |month=April |pmid=12698518 |doi= |url=http://www.cmj.hr/2003/44/2/12698518.pdf]

Eponym

It is named for Bernhard Riedel. He first recognized the disease In 1883 and published its description in 1896. [B. M. C. L. Riedel. Die chronische, zur Bildung eisenharter Tumoren führende Entzündung der Schilddrüse. Verhandlungen der deutschen Gesellschaft für Chirurgie, 1896, 25: 101-105.] [WhoNamedIt|synd|3242]

References