Kveim test

Kveim test

The Kveim test, Nickerson-Kveim or Kveim-Siltzbach test is a skin test used to detect sarcoidosis, where part of a spleen from a patient with known sarcoidosis is injected into the skin of a patient suspected to have the disease. If granulomas are found (4-6 weeks later), the test is positive. If the patient has been on treatment (e.g. glucocorticoids), the test may be false negative. The test is not commonly performed, and in the UK no substrate has been available since 1996. There is a concern that certain infections, such as bovine spongiform encephalopathy, could be transferred through a Kveim test. [GPnotebook|-389021680]

It is named for the Norwegian pathologist Morten Ansgar Kveim, who first reported the test in 1941 using lymph node tissue from sarcoidosis patients. [cite journal|author=Kveim MA|title=En ny og spesifikk kutan-reaksjon ved Boecks sarcoid. En foreløpig meddelelse|lang=Norwegian|journal=Nordisk Medicin|year=1941|volume=9|pages=169–172] [WhoNamedIt|synd|556] It was popularised by the American physician Louis Siltzbach, who introduced a modified form using spleen tissue in 1954. [cite journal |author=Siltzbach LE, Ehrlich JC |title=The Nickerson-Kveim reaction in sarcoidosis |journal=Am. J. Med. |volume=16 |issue=6 |pages=790–803 |year=1954 |pmid=13158367 |doi=] Kveim's work was a refinement of earlier studies performed by Nickerson, who in 1935 first reported on skin reactions in sarcoid. [cite journal|author=Williams R, Nickerson D|year=1935|title=Skin reactions in sarcoid|journal=Proc. Soc. Exp. Biol. Med. |volume=33|pages=402–405]

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Look at other dictionaries:

  • Kveim test — «kvaym», a skin test for the diagnosis of sarcoidosis. ╂[< M.A. Kveim, a Norwegian physician of the 1900 s] …   Useful english dictionary

  • Kveim-Test — Der Kveim Test (auch „Nickerson Kveim “ oder „Kveim Siltzbach Test“) ist ein medizinischer Hauttest, der zur Diagnostik bei Sarkoidoseverdacht eingesetzt wurde. Er wurde 1941 von dem Osloer Arzt Morten A. Kveim veröffentlicht, jedoch war ein… …   Deutsch Wikipedia

  • Kveim test — A skin test for detecting sarcoidosis, a disease of unknown origin that causes inflammation of body tissues, especially the lungs and skin. The Kveim test involves injecting a preparation derived from sarcoid tissue into the skin. A lump… …   Medical dictionary

  • Kveim-Test — Kve̲i̲m Test [kw...; nach dem norw. Arzt M.Kveim TestA. Kveim, geb.1892]: Untersuchungsmethode zur Diagnose der Sarkoidose (nach intrakutaner Injektion einer Suspension von sarkoidem Gewebe tritt bei positivem Ausfall ein derbes Knötchen an der… …   Das Wörterbuch medizinischer Fachausdrücke

  • Kveim test — a test used for the diagnosis of sarcoidosis. Tissue from a lymph node of a person suffering from the disease is injected intradermally; the development of a granuloma at the injection site indicates that the subject has sarcoidosis [A. Kveim… …   The new mediacal dictionary

  • Nickerson-Kveim test — See under test. * * * Kveim t …   Medical dictionary

  • test — 1. To prove; to try a substance; to determine the chemical nature of a substance by means of reagents. 2. A method of examination, as to determine the presence or absence of a definite disease or of some substance in any of the fluids, tissues,… …   Medical dictionary

  • Kveim — Morton A., Norwegian physician, *1892. See K. antigen, K. test, K. Siltzbach antigen, K. Siltzbach test, Nickerson K. test …   Medical dictionary

  • Morten Ansgar Kveim — (27 December 1892, Gjerstad – 24 March 1966) was a Norwegian pathologist remembered for describing the Kveim test. He qualified in medicine in 1925, and worked in a number of small towns in Norway. After 1929 he worked in the department of… …   Wikipedia

  • prueba de Nickerson-Kveim — Eng. Nickerson Kveim test Ver prueba de Kveim Stilzbach …   Diccionario de oftalmología

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