Tombusvirus 3' UTR region IV

Tombusvirus 3' UTR is an important cis-regulatory region of the Tombus virus genomecite journal | author = Fabian MR, Na H, Ray D, White KA | title = 3'-Terminal RNA secondary structures are important for accumulation of tomato bushy stunt virus DI RNAs | journal = Virology | volume = 313 | issue = 2 | pages = 567–80 | year = 2003 | pmid = 12954222 | doi = ] .

Tomato bushy stunt virus is the prototype member of the Tombusviridae family. The genome of this virus is positive sense single stranded RNA. Replication occurs via a negative strand RNA intermediate. In addition to viral proteins p33 and the RNA-dependent RNA polymerase p92, and unknown host factors, conserved and structural regions within the 3'untranslated region (3'UTR) are important for regulating genome replication. This 3' structural element contains a pseudoknot cite journal | author = Pogany J, Fabian MR, White KA, Nagy PD | title = A replication silencer element in a plus-strand RNA virus | journal = EMBO J. | volume = 22 | issue = 20 | pages = 5602–11 | year = 2003 | pmid = 14532132 | doi = 10.1093/emboj/cdg523] .

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