Small nucleolar RNA SNORD24

U24 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs [1] . C/D box snoRNAs have been shown to act as methylation guides for a number of RNA targets [2,3] . U24 is encoded within an intron of the gene for ribosomal protein L7a in mammals, chicken and Fugu [4] . The U76 snoRNA is found in an intron of the uRNA host gene (UHG) growth arrest specific 5 (GAS5) transcript gene [5] . snoRNAs Z20 and U76 snoRNAs show clear similarity to U24.

References

* [1] cite journal | last = Qu | first = LH | coauthors = Henry Y, Nicoloso M, Michot B, Azum MC, Renalier MH, Caizergues-Ferrer M, Bachellerie JP | year = 1995 | title = U24, a novel intron-encoded small nucleolar RNA with two 12 nt long, phylogenetically conserved complementarities to 28S rRNA | journal = Nucleic Acids Res | volume = 23 | pages = 2669–2676 | pmid = 7651828 | doi = 10.1093/nar/23.14.2669
* [2] cite journal | last = Nicoloso | first = M | coauthors = Qu LH, Michot B, Bachellerie JP | year = 1996 | title = Intron-encoded, antisense small nucleolar RNAs: the characterization of nine novel species points to their direct role as guides for the 2'-O-ribose methylation of rRNAs | journal = J Mol Biol | volume = 260 | pages = 178–195 | pmid = 8764399 | doi = 10.1006/jmbi.1996.0391
* [3] cite journal | last = Kiss-Laszlo | first = Z | coauthors = Henry Y, Bachellerie JP, Caizergues-Ferrer M, Kiss T | year = 1996 | title = Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs | journal = Cell | volume = 85 | pages = 1077–1088 | pmid = 8674114 | doi = 10.1016/S0092-8674(00)81308-2
* [4] cite journal | last = Gilley | first = J | coauthors = Fried M | year = 1998 | title = Evolution of U24 and U36 snoRNAs encoded within introns of vertebrate rpL7a gene homologs: unique features of mammalian U36 variants | journal = DNA Cell Biol | volume = 17 | pages = 591–602 | pmid = 9703018
* [5] cite journal | last = Hirose | first = T | coauthors = Steitz JA | year = 2001 | title = Position within the host intron is critical for efficient processing of box C/D snoRNAs in mammalian cells | journal = Proc Natl Acad Sci U S A | volume = 98 | pages = 12914–12919 | pmid = 11606788 | doi = 10.1073/pnas.231490998

External links

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