PrrF RNA

PrrF RNA

PrrF RNA is a small non-coding RNA involved in iron homeostasis and is found exclusively in Pseudomonas species. PrrF sequences are the functional homologues of RyhB RNA and are found in tandem. Their expression is induced under iron limitation by the ferric uptake regulator (Fur) and they act to negatively regulate several genes including sodB and sdh. [cite journal | last = Wilderman | first = PJ | coauthors = Sowa NA, FitzGerald DJ, FitzGerald PC, Gottesman S, Ochsner UA, Vasil ML | year = 2004 | title = Identification of tandem duplicate regulatory small RNAs in Pseudomonas aeruginosa involved in iron homeostasis | journal = Proc Natl Acad Sci U S A | volume = 101 | pages = 9792–9797 | pmid = 15210934 | doi = 10.1073/pnas.0403423101]

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