FinP

FinP encodes an antisense non-coding RNA gene that is complementary to part of the 5' UTR of the traJ mRNA. The FinOP system regulates the transfer of F-like plasmids. The traJ gene encodes a protein required for transcription from the major transfer promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from RNase E degradation.

References

* [1] cite journal | last = Jerome | first = LJ | coauthors = van Biesen T, Frost LS | year = 1999 | title = Degradation of FinP antisense RNA from F-like plasmids: the RNA-binding protein, FinO, protects FinP from ribonuclease E | journal = J Mol Biol | volume = 285 | pages = 1457–1473 | pmid = 9917389 | doi = 10.1006/jmbi.1998.2404
* [2] cite journal | last = Arthur | first = DC | coauthors = Ghetu AF, Gubbins MJ, Edwards RA, Frost LS, Glover JN | year = 2003 | title = FinO is an RNA chaperone that facilitates sense-antisense RNA interactions | journal = EMBO J | volume = 22 | pages = 6346–6355 | pmid = 14633993 | doi = 10.1093/emboj/cdg607

External links

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