Enterovirus 5' cloverleaf cis-acting replication element

The Enterovirus 5' cloverleaf cis-acting replication element is an RNA element found in the 5' UTR of Enterovirus genomes. The element has a cloverleaf like secondary structure and is known to be a multifunctional cis-acting replication element (CRE), required for the initiation of negative strand RNA synthesis. [cite journal | last = Barton | first = DJ | coauthors = O'Donnell BJ, Flanegan JB | year = 2001 | title = 5' cloverleaf in poliovirus RNA is a cis-acting replication element required for negative-strand synthesis | journal = EMBO J | volume = 20 | pages = 1439–1448 | pmid = 11250909 | doi = 10.1093/emboj/20.6.1439]

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