- Arthur Harden
Infobox_Scientist
name = Arthur Harden
image_size = 180px
birth_date = birth date|1865|10|12
birth_place =Manchester ,England
death_date = death date and age|1940|6|17|1865|10|12
death_place =Bourne End ,England
nationality =United Kingdom
field =Biochemistry
work_institution =
alma_mater =University of Manchester master,University of Erlangen phd
doctoral_advisor =Otto Fischer
doctoral_students =
known_for = the chemistry of theyeast cell
prizes =Nobel Prize in Chemistry (1929)Arthur Harden (
October 12 1865 –June 17 1940 ) was an Englishbiochemist . He shared theNobel Prize in Chemistry in 1929 withHans Karl August Simon von Euler-Chelpin for their investigations into the fermentation of sugar and fermentative enzymes.Biography
Harden was born on 12 October 1865 in
Manchester to Albert Tyas Harden and Eliza Macalister. He was educated at a private school and atTettenhall College ,Staffordshire , and enteredOwens College in theUniversity of Manchester in 1882, graduating in 1885. In 1886 he was awarded theDalton Scholarship in Chemistry and spent a year working withOtto Fischer atErlangen . He returned to Manchester as lecturer and demonstrator, and remained there until 1897 when he was appointed chemist to the newly foundedBritish Institute of Preventive Medicine , which later became theLister Institute . In 1907 he was appointed Head of the Biochemical Department, a position which he held until his retirement in 1930 (though he continued his scientific work at the Institute after his retirement).At Manchester Harden had studied the action of
light on mixtures ofcarbon dioxide andchlorine , and when he entered the Institute he applied his methods to the investigation of biological phenomena such as the chemical action of bacteria and alcoholic fermentation. He studied the breakdown products ofglucose and the chemistry of theyeast cell, and produced a series of papers on theantiscorbutic andantineuritic vitamin s.Harden was knighted in 1926, and received several honorary doctorates. A Fellow of the
Royal Society , he received theDavy Medal in 1935.He was married with no children. His wife died in 1928, and Sir Arthur died at his home in Bourne End,
Buckinghamshire on 17 June 1940.References
*cite journal | author=F. G. Hopkins; C. J. Martin | title=Arthur Harden. 1865-1940 | journal= Obituary Notices of Fellows of the Royal Society | year=1942 | volume=4 | issue=11 | pages=2–14 | url=http://links.jstor.org/sici?sici=1479-571X%28194211%294%3A11%3C2%3AAH1%3E2.0.CO%3B2-T3 | doi=10.1098/rsbm.1942.0001
*cite journal | quotes=yes | last=Manchester | first=K L | authorlink= | year=2000|month=. | title=Biochemistry comes of age: a century of endeavour | journal=Endeavour | volume=24 | issue=1 | pages=22–7 | publisher=| location= | pmid=10824440 | bibcode=| oclc =| id=| url=| language=| format=| accessdate=| laysummary=| laysource=| laydate=| quote=| doi=10.1016/S0160-9327(99)01224-7
*cite journal | quotes=yes | last=Manchester | first=K L | authorlink= | year=2000|month=Feb. | title=Arthur Harden: an unwitting pioneer of metabolic control analysis | journal=Trends Biochem. Sci. | volume=25 | issue=2 | pages=89–92 | publisher=| location= | pmid=10664590| doi=10.1016/S0968-0004(99)01528-5
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