Zieve's syndrome

Zieve's syndrome

Zieve's syndrome is an acute metabolic condition that can occur during withdrawal from prolonged alcohol abuse. It is defined by hemolytic anemia, hyperlipoproteinaemia (excessive blood lipoprotein), jaundice, and abdominal pain.cite book | last=Mehta | first=AB |coauthors=N McIntyre | title=Oxford Textbook of Clinical Hepatology | publisher=Oxford University Press | date=2004 | pages=1786–1787 | isbn=0-19-262515-2 ] The underlying cause is liver delipidization. This is distinct from alcoholic hepatitis, which however may be subsequent or copresent.

History

Zieve's syndrome was initially described in 1958.cite journal | last=Zieve | first=L | title=Jaundice, hyperlipemia and hemolytic anemia: a heretofore unrecognized syndrome associated with alcoholic fatty liver and cirrhosis | journal=Annals of Internal Medicine | volume=48 | pages=471–476 | date=March 1958 | pmid=13521581 ] Dr Zieve described patients with a combination of alcoholic liver disease, hemolytic anemia and [hypertriglyceridemia]

References


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