FIS (protein)

FIS (protein)

FIS is a nucleoid-associated protein in "E. coli". It is highly expressed from "fis" gene from the end of the stationary phase till the mid-exponential phase. It is a DNA binding protein. It affects the topology and supercoiling of "E. coli" chromosome, and it regulates the expression of many other genes.

References

Travers, A.; Schneider, R.; Muskhelishvil, G. DNA supercoiling and transcription in "Escherichia coli": The FIS connection. Biochimie, 2001.


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