Worster-Drought syndrome

This article is about the form of cerebral palsy. For the type of dementia also known as Worster-Drought syndrome, see Familial British dementia.

Worster-Drought syndrome is a form of congenital suprabulbar paresis that occurs in some children with cerebral palsy. It is caused by inadequate development of the corticobulbar tracts and causes problems with the mouth and tongue including impaired swallowing.^[1] A similar syndrome in adults is called anterior opercular syndrome.^[1][2]

A 1986 study of a family in which multiple members had Worster-Drought Syndrome suggested it might be hereditary.^[3]

A 2000 review of cases classified Worster-Drought Syndrome as a form of cerebral palsy, caused by early damage to the brain, but identified no obvious causes during gestation or birth and found some families with a history of the condition.^[4]

The syndrome was named after Cecil Charles Worster-Drought, the doctor who discovered it in 1956.

References

1. ^ ^{a b} Suresh PA, Deepa C (September 2004). "Congenital suprabulbar palsy: a distinct clinical syndrome of heterogeneous aetiology". Developmental Medicine and Child Neurology 46 (9): 617–25. doi:10.1111/j.1469-8749.2004.tb01026.x. PMID 15344522. 
2. ^ Christen HJ, Hanefeld F, Kruse E, Imhäuser S, Ernst JP, Finkenstaedt M (February 2000). "Foix-Chavany-Marie (anterior operculum) syndrome in childhood: a reappraisal of Worster-Drought syndrome". Developmental Medicine and Child Neurology 42 (2): 122–32. doi:10.1017/S0012162200000232. PMID 10698330. 
3. ^ Patton MA, Baraitser M, Brett EM (February 1986). "A family with congenital suprabulbar paresis (Worster-Drought syndrome)". Clinical Genetics 29 (2): 147–50. doi:10.1111/j.1399-0004.1986.tb01239.x. PMID 3955865. 
4. ^ Clark M, Carr L, Reilly S, Neville BG (October 2000). "Worster-Drought syndrome, a mild tetraplegic perisylvian cerebral palsy. Review of 47 cases". Brain 123 (10): 2160–70. doi:10.1093/brain/123.10.2160. PMID 11004132. 

Sources

• Worster-Drought C (August 1956). "Congenital suprabulbar paresis". The Journal of Laryngology and Otology 70 (8): 453–63. doi:10.1017/S0022215156000115. PMID 13357872. 
• Malcolm Ray McNeil, Clinical Management of Sensorimotor Speech Disorders, New York: Thieme, 1997, p. 407.
• Bianca Specht-Moser, "Die Behandlung des Kausystems in der Kinder- und Jugendneurorehabilitation - Elemente eines Rehabilitationspfades" MS Thesis, Danube University Krems, September 2004 (pdf, German)

External links

• Worster-Drought Syndrome Support Group
• Castillo-Morales Vereinigung English homepage - holistic therapy
• Padovan Speech Therapy
• Worster-Drought Syndrome Support Group twitter page