Anatoxin-a

Anatoxin-a

Chembox new
ImageFile=Anatoxin-a.pngImageSize=150px
IUPACName=1- [(1R,6R)-9-azabicyclo [4.2.1] non-4-en-5-yl] ethanone
OtherNames=Anatoxin A
Section1= Chembox Identifiers
CASNo=64285-06-9
PubChem=3034748
SMILES=CC(=O)C1=CCCC2CCC1N2

Section2= Chembox Properties
Formula=C10H15NO
MolarMass=165.232
Appearance=
Density=
MeltingPt=
BoilingPt=
Solubility=

Section3= Chembox Hazards
MainHazards=
FlashPt=
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Anatoxin-a is a secondary, bicyclic amine alkaloid and cyanotoxin with acute neurotoxicity. The toxin is produced by at least four different genera of cyanobacteria and has been reported in North America, Europe, Africa, Asia, and Australia. Symptoms of anatoxin exposure are loss of coordination, muscular fasciculations, convulsions and death by respiratory paralysis. Its mode of action is through the nicotinic acetylcholine receptor where it acts as an analogue of acetylcholine. The molecule is not degraded by cholinesterase thus causes permanent stimulation of muscle cells leading to paralysis. Information on carcinogenicity is not available.

References

*Wood, S. A., J. P. Rasmussen, P. T. Holland, R. Campbell, and A. L. M. Crowe. 2007. "First Report of the Cyanotoxin Anatoxin-A from Aphanizomenon issatschenkoi (cyanobacteria)" "Journal of Phycology" 43:356-365.
*National Center for Environmental Assessment. "Toxicological Reviews of Cyanobacterial Toxins: Anatoxin-a" NCEA-C-1743


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  • Anatoxin — A|na|to|xin [↑ ana (1) u. ↑ Toxin] svw. ↑ Toxoid. * * * Anatoxin   [griechisch] das, s/ e, Toxoid, Formoltoxoid, durch Formalineinwirkung entgiftetes Bakteriengift …   Universal-Lexikon

  • anatoxin — n. [Gr. ana, backwards; toxikon, poison] A toxin modified by heat or chemical treatment eliminating its toxic properties, but retaining its antigenic properties; toxoid …   Dictionary of invertebrate zoology

  • anatoxin — /an euh tok sin/, n. toxoid. [1920 25; ANA + TOXIN] * * * …   Universalium

  • anatoxin — noun Any of a group of neurotoxins produced by several species of cyanobacterium …   Wiktionary

  • anatoxin — SYN: toxoid. * * * ana·tox·in .an ə täk sən n TOXOID * * * n. a former name for toxoid. * * * ana·tox·in (anґə tok″sin) [ana + toxin] toxoid. anatoxic adj …   Medical dictionary

  • Anatoxin — Ana|toxi̱n [↑ana... u. ↑Toxin] s; s, e: entgiftetes, aber noch Immunisierung bewirkendes ↑Toxin …   Das Wörterbuch medizinischer Fachausdrücke

  • Anatoxin — Ana|to|xin das; s, e <zu ↑ana... u. ↑Toxin> durch Formalineinwirkung entgiftetes Bakteriengift, das zur Schutzimpfung dient …   Das große Fremdwörterbuch

  • anatoxin — n. toxoid, toxin no longer poisonous but able to cause antigen production …   English contemporary dictionary

  • anatoxin — an·a·tox·in …   English syllables

  • anatoxin — n. a former name for toxoid …   The new mediacal dictionary

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