Lymphoblast

Lymphoblast

Lymphoblasts are immature cells which typically differentiate to form mature lymphocytes. Normally lymphoblasts are found in the bone marrow, but in acute lymphoblastic leukemia (ALL), lymphoblasts proliferate uncontrollably and are found in large numbers in the peripheral blood.

Although commonly lymphoblast refers to a precursor cell in the maturation of leukocytes, the usage of this term is sometimes inconsistent. The Chronic Lymphocytic Leukemia Research Consortium defines a lymphoblast as "A lymphocyte that has become larger after being stimulated by an antigen. Lymphoblasts look like immature lymphocytes, and were once thought to be precursor cells." [ [http://cll.ucsd.edu/glossaryl.htm CRC - Glossary L ] ] . Commonly, when speaking about leukemia, "blast" is used as an abbreviation for lymphoblasts.


=Additional

They are 2.5 micrometres in size.

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Look at other dictionaries:

  • lymphoblast — [lim′fō blast΄] n. [ LYMPHO + BLAST] a primitive cell that is a precursor of a lymphocyte …   English World dictionary

  • lymphoblast — Often referred to as a blast cell. Unlike other usages of the suffix blast a lymphoblast is a further differentiation of a lymphocyte, T or B , occasioned by an antigenic stimulus. The lymphoblast usually develops by enlargement of a lymphocyte,… …   Dictionary of molecular biology

  • lymphoblast — A lymphocyte that has gotten larger after being stimulated by an antigen. Lymphoblast also refers to an immature cell that can develop into a mature lymphocyte …   English dictionary of cancer terms

  • lymphoblast-like — adjective resembling a lymphoblast • Similar to: ↑cellular …   Useful english dictionary

  • lymphoblast — noun Etymology: International Scientific Vocabulary Date: circa 1909 a lymphocyte that has enlarged following stimulation by an antigen, has the capacity to recognize the stimulating antigen, and is undergoing proliferation and differentiation… …   New Collegiate Dictionary

  • Lymphoblast — REM Bild eines Lymphozyten Lymphozyten (Singular der Lymphozyt) sind zelluläre Bestandteile des Blutes. Sie umfassen die B Zellen, T Zellen und die natürlichen Killerzellen und gehören zu den sogenannten „weißen Blutkörperchen“ (Leukozyten). Bei… …   Deutsch Wikipedia

  • lymphoblast — lymphoblastic, adj. /lim feuh blast /, n. Cell Biol. a large, metabolically active lymphocyte shortly before it enters into mitosis. [1905 10; LYMPHO + BLAST] * * * ▪ cell       immature white blood cell (leukocyte) that gives rise to a type of… …   Universalium

  • lymphoblast — noun An immature lymphocyte; they proliferate uncontrollably in lymphoblastic leukemia …   Wiktionary

  • lymphoblast — A young immature cell that matures into a lymphocyte and is characterized by more abundant cytoplasm than in a lymphocyte, a nucleus in which the chromatin is finer than in a lymphocyte (but coarser than in a myeloblast), and one or two rather… …   Medical dictionary

  • Lymphoblast — Lym|pho|blạst [↑Lymphe u. ↑...blast] m; en, en (meist Mehrz.): Jugendform der ↑Lymphozyten …   Das Wörterbuch medizinischer Fachausdrücke

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