John Jacob Abel

John Jacob Abel

Infobox Scientist
name = John Jacob Abel
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caption = John Jacob Abel
birth_date = May 19, 1857
birth_place = Cleveland, Ohio
death_date = May 26, 1938
death_place =
residence =
citizenship =
nationality = American
ethnicity =
field = biochemist pharmacologist
work_institutions =
alma_mater = University of Michigan
doctoral_advisor =
doctoral_students =
known_for =
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John Jacob Abel (May 19, 1857May 26, 1938) was a significant American biochemist and pharmacologist.

Born near Cleveland, Ohio, he graduated with a Ph.D. 1883 from the University of Michigan. In 1891 he founded and chaired the first department of pharmacology in the United States at the University of Michigan. In 1893, he went on to chair the pharmacology department at Johns Hopkins University. In 1897, he was the second to isolate epinephrine, also known as adrenaline (the first was Napoleon Cybulski in 1895), although the extracts he produced have been shown to be mostly an inactive metabolite and the first pure extracts were produced by the Japanese Jokichi Takamine (1854-1922) who patented the formulation under the name adrenalin. He later formulated the idea of the artificial kidney and in 1914 he isolated amino acids from the blood.

He spent years unsuccessfully searching for the pituitary hormone, unaware that he was in fact looking for several hormones. In 1926, he reported the isolation and crystallization of insulin, though this announcement was met with considerable scepticism and not generally accepted for many years.

Abel also co-founded the "Journal of Biological Chemistry" with Christian Archibald Herter in 1905 and the "Journal of Pharmacology and Experimental Therapeutics" in 1909.

References

*Citation
id = PMID:3517604
url= http://www.ncbi.nlm.nih.gov/pubmed/3517604
last=Gastel
first=B
publication-date=
year=
title=Abel and onward: some early history of hemodialysis.
volume=20
issue=2
periodical=Medical instrumentation
pages=62-4

*Citation
id = PMID:11615884
url= http://www.ncbi.nlm.nih.gov/pubmed/11615884
last=Becker
first=R A
publication-date=1982
year=1982
title=The John Jacob Abel papers--primary sources for the history of American pharmacology.
volume=24
issue=3
periodical=Pharmacy in history
pages=115-6

*Citation
id = PMID:6760940
url= http://www.ncbi.nlm.nih.gov/pubmed/6760940
last=Parascandola
first=J
publication-date=1982
year=1982
title=John J. Abel and the early development of pharmacology at the Johns Hopkins University.
volume=56
issue=4
periodical=Bulletin of the history of medicine
pages=512-27

*Citation
id = PMID:801548
url= http://www.ncbi.nlm.nih.gov/pubmed/801548
last=Harvey
first=A M
publication-date=1976
year=1976
title=Pharmacology's giant: John Jacob Abel.
volume=
issue=
periodical=Johns Hopkins Med. J. Suppl.
pages=49-59

*Citation
id = PMID:4606906
url= http://www.ncbi.nlm.nih.gov/pubmed/4606906
last=Harvey
first=A M
publication-date=1974 Oct
year=1974
title=Pharmacology's giant: John Jacob Abel.
volume=135
issue=4
periodical=The Johns Hopkins medical journal
pages=245-58

* Rosenberg, Charles. "Abel, John Jacob." in "Dictionary of Scientific Biography." (1970). New York: Charles Scribner's Sons. Vol. 1: p.9-12.
*Citation
id = PMID:5340582
url= http://www.ncbi.nlm.nih.gov/pubmed/5340582
last=Murnaghan
first=J H
last2=Talalay
first2=P
publication-date=1967
year=1967
title=John Jacob Abel and the crystallization of insulin.
volume=10
issue=3
periodical=Perspect. Biol. Med.
pages=334-80

*Citation
id = PMID:14118479
url= http://www.ncbi.nlm.nih.gov/pubmed/14118479
last=DARBY
first=T D
publication-date=1964 Feb
year=1964
title=ON TEACHING PHARMACOLOGY AND THERAPEUTICS IN OUR MEDICAL SCHOOLS. DELIBERATION UPON AND A REPHRASING OF AN ARTICLE BY JOHN J. ABEL.
volume=67
issue=
periodical=Am. Heart J.
pages=145-9

*Citation
id = PMID:13979597
url= http://www.ncbi.nlm.nih.gov/pubmed/13979597
last=SWAIN
first=H H
last2=Geiling
first2=E M
last3=Heingartner
first3=A
publication-date=
year=
title=John Jacob ABEL at Michigan. The introduction of pharmacology into the medical curriculum.
volume=29
issue=
periodical=Medical bulletin (Ann Arbor, Mich.)
pages=1-14

*Citation
id = PMID:13573011
url= http://www.ncbi.nlm.nih.gov/pubmed/13573011
last=MARSHALL
first=E K
publication-date=
year=
title=An exhibit at the centennial celebration of John Jacob Abel's birth.
volume=32
issue=4
periodical=Bulletin of the history of medicine
pages=356-65

*Citation
id = PMID:13489405
url= http://www.ncbi.nlm.nih.gov/pubmed/13489405
last=SOLLMAN
first=T
last2=AMBERG
first2=S
last3=VOEGTLIN
first3=C
last4=ROWNTREE
first4=L G
publication-date=1957 Dec
year=1957
title=Centenary of the birth of John Jacob Abel.
volume=101
issue=6
periodical=Bulletin of the Johns Hopkins Hospital
pages=298-328


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  • John Jacob Abel — (* 19. Mai 1857 in Cleveland, Ohio; † 26. Mai 1938 in Baltimore, Maryland) war ein US amerikanischer Biochemiker und Pharmakologe. Inhaltsverzeichnis 1 Leben und Werk 2 Bedeutende Schriften …   Deutsch Wikipedia

  • John Jacob Abel — (Cleveland, 19 de mayo de 1857 – Baltimore,26 de mayo de 1938)Quimico y farmacólogo estadounidense, cuyas investigaciones supusieron importantes avances en el campo de la farmacología. Se graduó en la Universidad de Míchigan en 1883 como experto… …   Wikipedia Español

  • Abel , John Jacob — (1857–1938) American biochemist Abel was born in Cleveland, Ohio, the son of a farmer. He was educated at the University of Michigan and Johns Hopkins University. He spent the years 1884–90 in Europe studying at Leipzig, Heidelberg, Würzburg,… …   Scientists

  • Abel, John Jacob — ▪ American physiological chemist born May 19, 1857, Cleveland, Ohio, U.S. died May 26, 1938, Baltimore, Md.       American pharmacologist and physiological chemist who made important contributions to a modern understanding of the ductless, or… …   Universalium

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  • Abel (surname) — Family name name = Abel imagesize= caption= pronunciation = meaning = breath from the given name Abel, the second son of Adam and Eve region = origin = Biblical related names =Aapeli footnotes =Abel is a surname, and may refer to: * Alan Abel (b …   Wikipedia

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  • Abel (homonymie) — Cette page d’homonymie répertorie les différents sujets et articles partageant un même nom. Sur les autres projets Wikimedia : « Abel (homonymie) », sur le Wiktionnaire (dictionnaire universel) Abel est un nom propre qui peut… …   Wikipédia en Français

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  • Abel (Son of Adam) —     Abel     † Catholic Encyclopedia ► Abel     (From the Hebrew word for Vanity, probably so called from the shortness of his life Gesenius; Gr., Abel, whence Eng. form).     Abel was the second son of Adam. Vigouroux and Hummelauer contend that …   Catholic encyclopedia

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