James Shapiro (disambiguation)
- James Shapiro (disambiguation)
James Shapiro may refer to:
* Jim Shapiro, American attorney
* Jim Shapiro (drummer) (born 1965), American rock musician
* James Shapiro, British-born Canadian doctor who developed the Edmonton protocol
* James A. Shapiro, American professor of biochemistry and molecular biology
* James S. Shapiro (born 1955), American professor of English and comparative literature, non-fiction author
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