Transfusion hemosiderosis

Transfusion hemosiderosis

Infobox_Disease
Name = PAGENAME


Caption =
DiseasesDB =
ICD10 = ICD10|T|80|8|t|80
ICD9 = ICD9|999.8
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj =
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Transfusional hemosiderosis is the accumulation of iron in the liver and/or heart but also endocrine organs, in patients who receive frequent blood transfusions (such as those with thalassemia, sickle cell disease, aplastic anemia or myelodysplastic syndrome).

Treatment

Treatment is by iron chelating agents: deferoxamine,cite journal |author=Cappellini MD |title=Exjade(R) (deferasirox, ICL670) in the treatment of chronic iron overload associated with blood transfusion |journal=Ther Clin Risk Manag |volume=3 |issue=2 |pages=291–9 |year=2007 |month=June |pmid=18360637 |doi= |url=] deferiprone or deferasirox. If iron overload has caused end-organ damage, this is generally irreversible and may require transplantation.

Notable patients

Ted DeVita, the "bubble boy", died of transfusional iron overload from too many blood transfusions.

See also

* Hemosiderosis

References


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