Spinal Muscular Atrophy Type 2
- Spinal Muscular Atrophy Type 2
Spinal Muscular Atrophy Type 2 (also known as "spinal muscular atropy type II") is an autosomal recessive disease and is a form of spinal muscular atrophy (SMA).
Symptoms
Children with spinal muscular atrophy type 2 manifest less severe weakness than children with Werdnig-Hoffman disease. Symptoms are usually noticed later in life, usually between the age of 6 to 18 months. The clinical features are similar to those found in children with Type 1; in fact, there are many children for whom the characterization of Type 1 (Werdnig-Hoffman) or Type 2 SMA becomes a "best guess". Children with Type 2 SMA usually achieve the ability to sit independently, however, they almost never achieve the ability to walk or stand without support.
Prognosis
Some children with SMA Type 2 have a relatively static course and remain free of life threatening complications such as pneumonia. Other children, have progressive weakness of their swallowing and respiratory muscles. Many youngsters with SMA Type 2 develop curvature of the spine (Kyphoscoliosis) and other orthopedic problems. Skillful management by a team of physical therapists and orthopedic surgeons is usually needed to manage these problems.
ee also
* Motor neurone disease
* Spinal Muscular Atrophy
* Kugelberg-Welander disease
* Werdnig-Hoffman disease
Source
* [http://www.fightsma.org/index.php?sma-guidebook Fight SMA Spinal Muscular Atrophy Guidebook]
External links
* [http://www.fightsma.org Fight SMA / Spinal Muscular Atrophy]
*
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