Sticky mouse syndrome

Sticky mouse syndrome

Sticky mouse syndrome is a genetic disorder found in mice, caused by defective aminoacyl tRNA synthetase. Its most immediately obvious symptom is a sticky secretion on the mouse's fur (thus the name); however, it is accompanied by lack of muscle control, ataxia, alopecia, loss of Purkinje cells in the cerebellum, and eventually, death. [http://www.cprmap.com/neurodegenerative-brain-diseases/mischarged-trnas-lead-protein-misfolding-neurodegenerative-disease-16698.html]

Notes

References

*Lee et al, Nature, Aug 13, 2006.


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