Adenine nucleotide translocator
- Adenine nucleotide translocator
protein
Name=solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
caption=
width=
HGNCid=10990
Symbol=SLC25A4
AltSymbols=PEO3, PEO2, ANT1
EntrezGene=291
OMIM=103220
RefSeq=NM_001151
UniProt=P12235
PDB=
ECnumber=
Chromosome=4
Arm=q
Band=35
LocusSupplementaryData=protein
Name=solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
caption=
width=
HGNCid=10991
Symbol=SLC25A5
AltSymbols=ANT2
EntrezGene=292
OMIM=300150
RefSeq=NM_001152
UniProt=P05141
PDB=
ECnumber=
Chromosome=X
Arm=q
Band=24
LocusSupplementaryData=-q26protein
Name=solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
caption=
width=
HGNCid=10992
Symbol=SLC25A6
AltSymbols=ANT3
EntrezGene=293
OMIM=403000
RefSeq=NM_001636
UniProt=P12236
PDB=
ECnumber=
Chromosome=Y
Arm=p
Band=
LocusSupplementaryData=
Adenine nucleotide translocator (ANT) also known as the ADP/ATP translocator is a mitochondrial protein.
Function
ANT functions as a homodimer of subunits asymmetrically in the inner mitochondrial membrane. This dimer forms a gated pore through which ADP and ATP is exchanged between the mitochondrial matrix and the cytoplasm.
Types
In humans, there exist three paraologous ANT isoforms:
* SLC25A4 – found primarily in heart and skeletal muscle
* – primarily expressed in fibroblasts
* – primarily express in liver
ee also
* mitochondrial carrier
External links
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Wikimedia Foundation.
2010.
Look at other dictionaries:
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