Dantron

Drugbox
IUPAC_name = 1,8-dihydroxyanthracene-9,10-dione

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CAS_number = 117-10-2
ChemSpiderID = 2845
ATC_prefix = A06
ATC_suffix = AB03
ATC_supplemental = ATC|A06|AB53 ATC|A06|AG03
PubChem = 2950
DrugBank =
C=14|H=8|O=4
molecular_weight = 240.211 g/mol
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routes_of_administration = Oral, rectal (enema):"Dantron" is also a trade name of ondansetron, an unrelated drug, in South Africa."Dantron (also known as chrysazin) is an anthraquinone derivative, 1,8-dihydroxyanthraquinone, used in some countries as a stimulant laxative. In the USA it is considered to be a carcinogen, [ [http://ntp.niehs.nih.gov/ntp/roc/eleventh/profiles/s055dant.pdf Danthron substance profile] at the National Toxicology Program website] and is therefore not used. In the UK it is considered a possible carcinogen and so its licence is restricted to patients who already have a diagnosis of terminal cancer (i.e. it is mainly used in palliative care to counteract the constipating effects of opioids)

It has the notable side-effect of causing red-coloured urine.

Danthron was the British Approved Name, but it has now been changed to "dantron" in harmony with the recommended International Nonproprietary Name (rINN).

References