Irvine Page

Irvine Heinly Page (January 7, 1901 - June 10, 1991) was born in Indianapolis, Indiana and was an American physiologist who played an important part in the field of hypertension for almost 60 years. [Dustan HP. "Irvine Page lecture. Legacies of Irvine H. Page." J Hypertens Suppl. 1990;8:S29-34. PMID 2095393.] [Dustan HP " [http://books.nap.edu/readingroom/books/biomems/ipage.pdf Irvine Heinly Page.] " The National Academies Press Biographical Memoirs.] [Frohlich ED, Dustan HP, Bumpus FM " [http://hyper.ahajournals.org/cgi/reprint/18/4/443.pdf Irvine H. Page: 1901-1991. The Celebration of a Leader] " Hypertension 1991;18:443-445.]

His first contributions were published in the early 1930s and his most recent, "Hypertension Research: A Memoir : 1920-1960", in 1988. He is perhaps best know for the co-discovery of serotonin in 1948, [Rapport MM, Green AA, Page IH (1948). "Serum vasoconstrictor (serotonin). IV. Isolation and characterization". "J Biol Chem" 176 (3): 1243–1251.] although his pre-eminence is a matter of record in four other areas: the renin-angiotensin system, the mosaic theory of hypertension, [Page IH (1967). "The mosaic theory of arterial hypertension--its interpretation." Perspect Biol Med. 10:325-33.PMID 6034593.] treatment of hypertension and public and professional advocacy of the recognition of this condition and its effects in daily life. In earlier work he published on the neurochemistry of the brain.

Page received many honors for his work. He was president of the American Heart Association (1956-57); he received ten honorary degrees and a number of prestigious awards--the Ida B. Gould Memorial Award of the American Association for the Advancement of Science (1957); Albert Lasker Award (1958); Gairdner Foundation Award (1963); Distinguished Award of the American Medical Association (1964); Oscar B. Hunter Award (1966); Passano Foundation Award (1967); and the Stouffer Prize (now the Novartis Award) for Hypertension Research in 1970. He was elected to the National Academy of Sciences in 1971 and published his memoirs in 1988.

The American Heart Association [http://www.heart.org/presenter.jhtml?identifier=3041097 Irvine H. Page Young Investigator Research Award] and the [http://www.americanheart.org/presenter.jhtml?identifier=491 Irvine Page - Alva Bradley Lifetime Achievement Award] are named in his honor.

Footnotes

Bibliography

*cite book|last=Page|first=Irvine|title=Hypertension Mechanisms|year=1987|publisher=Grune & Stratton|location=Orlando, Fla.|id=ISBN 0-808-91768-4
*cite book|last=Page|first=Irvine|title=Hypertension Research: A Memoir : 1920-1960|year=1988|publisher=Pergamon|location=New York|id=ISBN 0-080-36079-3
*cite book|last=Page|first=Irvine|title=Chemistry of the brain|year=1937|publisher=C.C. Thomas|location=New York|id=ASIN B-000-87D23-C