Genetic regulatory circuit
- Genetic regulatory circuit
Genetic regulatory circuits (also referred to as transcriptional regulatory circuits) are functional clusters of genes that impact each other's expression through inducible transcription factors and cis-regulatory elements. These circuits can be modeled "in silico" to predict the dynamics of a genetic system.
Understanding of genetic regulatory circuits are key in the field of synthetic biology, where disparate genetic elements are combined to produce novel biological functions.
Genetic regulatory circuits are analogous in many ways to electronic circuits.
References
* [http://genomebiology.com/2004/5/2/206 "Rewiring the transcriptional regulatory circuits of cells"] , "Genome Biology"
* [http://www.genesdev.org/cgi/content/full/18/4/357 "Transcriptional regulatory circuits controlling mitochondrial biogenesis and function"] , "Genes & Development"
* [http://www.ipam.ucla.edu/abstract.aspx?tid=4751 "Structure and function of genetic regulatory circuits in Escherichia coli"] , Michael Wall, Los Alamos National Laboratory
Wikimedia Foundation.
2010.
Look at other dictionaries:
Long non-coding RNA — Long noncoding RNAs (long ncRNAs) are generally considered (somewhat arbitrarily) as non protein coding transcripts longer than 200 nucleotides. This limit is due to practical considerations including the separation of RNAs in common experimental … Wikipedia
Competence (biology) — In microbiology, genetics, cell biology and molecular biology, competence is the ability of a cell to take up extracellular ( naked ) DNA from its environment. Competence is distinguished into natural competence , a genetically specified ability… … Wikipedia
Natural competence — In microbiology, genetics, cell biology and molecular biology, competence is the ability of a cell to take up extracellular ( naked ) DNA from its environment. Competence may be differentiated between natural competence, a genetically specified… … Wikipedia
Michael Elowitz — Michael B Elowitz is a biologist and professor of Biology and Applied Physics at the California Institute of Technology,[1][2][3] and investigator at the Howard Hughes Medical Institute.[4] In 2007 he was the recipient of the Genius grant, better … Wikipedia
Microbial cooperation — Microorganisms engage in a wide variety of social interactions, including cooperation. A cooperative behavior is one that benefits an individual (the recipient) other than the one performing the behavior (the actor).[1] This article outlines the… … Wikipedia
Artificial development — (also known as artificial embryogeny or computational development) is an area of computer science and engineering concerned with computational models motivated by genotype phenotype mappings in biological systems. Artificial development is often… … Wikipedia
Pseudomonas aeruginosa — P. aeruginosa on an XLD agar plate. Scientific classification Kingdom … Wikipedia
Klotho (biology) — protein Name=klotho caption= width= HGNCid=6344 Symbol=KL AltSymbols= EntrezGene=9365 OMIM=604824 RefSeq=NM 004795 UniProt=Q9UEF7 PDB= ECnumber= Chromosome=13 Arm=q Band=12 LocusSupplementaryData=The Klotho gene codes for a transmembrane protein… … Wikipedia
Nobel Prizes — ▪ 2009 Introduction Prize for Peace The 2008 Nobel Prize for Peace was awarded to Martti Ahtisaari, former president (1994–2000) of Finland, for his work over more than 30 years in settling international disputes, many involving ethnic,… … Universalium
Economic Affairs — ▪ 2006 Introduction In 2005 rising U.S. deficits, tight monetary policies, and higher oil prices triggered by hurricane damage in the Gulf of Mexico were moderating influences on the world economy and on U.S. stock markets, but some other… … Universalium
